Phenolics from Brazilian Propolis

Boudourova-Krasteva, G.; Bankova, Vassya; Sforcin, José Maurício; Nikolova, N; Попов, Симеон

doi:10.1515/znc-1997-9-1016

Cited by 52 publications

(43 citation statements)

References 11 publications

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“…Myricetin 3,7,4',5'-tetramethyl 11 ether and quercetin 3,7,3'-trimethyl ether 12 were isolated from Tunisian propolis, which originated from leaf exudates of Cistus species [34]. In Brazilian samples, kaempferid, 5,6,7-trihydroxy-3,4'-dihydroxyflavon 13, aromadendrine-4'methyl ether 14 [14] and 3,5,7-trihydroxy-6,4'-dimethoxyflavon 15 [9] were identified.…”

Section: Flavonoidsmentioning

confidence: 99%

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Propolis: recent advances in chemistry and plant origin

Castro²,

2000

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Section: Flavonoidsmentioning

confidence: 99%

“…Another class of phenolics newly found in Brazilian bee-glue, are prenylated p-coumaric acids and their derivatives with cyclized prenyl residues: 16-22 [1,9,14,39,47].…”

Section: Prenylated P-coumaric Acids and Acetophenonesmentioning

confidence: 99%

Propolis: recent advances in chemistry and plant origin

Castro²,

2000

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“…Telefax: (+5514) 3811-7189, E-mail: orsi@fca.unesp.br compounds (flavonoids, aromatic acids, benzopyranes), di-and triterpenes, essential oils, among others. Seasonal variations in propolis composition are not significant and are predominantly quantitative (2,4,6).…”

Section: Introductionmentioning

confidence: 99%

Synergistic effect of propolis and antibiotics on the Salmonella Typhi

Orsi¹,

Sforcin²,

Funari³

et al. 2006

Braz. J. Microbiol.

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The goal of this work was to investigate a possible synergistic effect between ethanolic extracts of propolis from Brazil and Bulgaria and some antibiotics (Amoxicillin, Ampicillin and Cefalexin) against Salmonella Typhi. Brazilian and Bulgarian propolis showed an antibacterial action, but the sample from Bulgaria was shown to be more efficient. Both samples showed a similar synergistic effect with these antibiotics. One may conclude that the propolis samples show an important antibacterial action, as well as a synergistic effect with antibiotics against Salmonella Typhi.

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“…Previous reports of our group revealed that propolis (100 mg/kg) decreased by 55% the cholesterol levels of hypercholesterolemia-induced rabbits (14). Free fatty acids were significantly decreased at the 21 st day in P10 group ( Figure 1 -B).…”

Section: Resultsmentioning

confidence: 58%

Propolis effect on streptozotocin-induced diabetic rats

Sartori¹,

Kawakami²,

Orsatti³

et al. 2009

J. Venom. Anim. Toxins incl. Trop. Dis

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ABSTRACT:Propolis is one of the hive products that has been used extensively in folk medicine, due to its several biological and pharmacological properties. Besides, propolis-containing products have been intensely marketed by the pharmaceutical industry and health-food stores. This work was carried out in order to investigate whether propolis treatment could revert the metabolic alterations of streptozotocininduced diabetic rats. Animals were kept in metabolic cages and diabetes was induced by a single dose of streptozotocin (35 mg/kg, IV). After a week, rats with glycemia higher than 230 mg/dL were divided into two groups and treated with ethanolic extract of propolis (10 and 90 mg/kg, PO) for seven days. Glycemia and free fatty acids were determined, as well as food and water intake, body weight and urine volume were registered weekly. Data showed no significant differences in the analyzed variables. Based on these results, one may conclude that propolis had no effects after diabetes establishment, in our conditions assays. Further assays with different concentrations of propolis and periods of administration should be carried out in order to evaluate its therapeutic potential in this disease. KEY WORDS:Brazilian propolis, diabetes, glucose, free fatty acids. CONFLICTS OF INTEREST:There is no conflict. CORRESPONDENCE TO:JOSÉ MAURÍCIO SFORCIN, Departamento de Microbiologia e Imunologia, Instituto

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Phenolics from Brazilian Propolis

Abstract: The main phenolic constituents from Brazilian propolis, originating from Sao Paulo State, were isolated and identified: three flavonoids, a prenylated coumaric acid and two new benzopyranes, E and Z 2,2-dimethyl-6-carboxyethenyl-8-prenyl-2H-benzopyranes

Cited by 52 publications

References 11 publications

Propolis: recent advances in chemistry and plant origin

Propolis: recent advances in chemistry and plant origin

Synergistic effect of propolis and antibiotics on the Salmonella Typhi

Propolis effect on streptozotocin-induced diabetic rats

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