Phomapyrones from blackleg causing phytopathogenic fungi: isolation, structure determination, biosyntheses and biological activity

Pedras, M. Soledade C.; Chumala, Paulos

doi:10.1016/j.phytochem.2004.10.011

Cited by 41 publications

(24 citation statements)

References 16 publications

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“…11 It was recently confirmed that the 2-pyrones isolated from fungi are of polyketide origin and those from marine mollusc are polypropionates. 12 Compounds 3 and 5 were identified on the basis of 1D and 2D NMR and FABMS data as phomapyrones B and C, respectively, which have previously been isolated from the blackleg fungus Phoma lingam. 8 Kojic acid (6) is a common microbial metabolite produced by Aspergillus, 13 Penicillium, 14 and Alternaria spp.…”

Section: Resultsmentioning

confidence: 99%

α-Pyrones and Yellow Pigments from the Sponge-Derived Fungus Paecilomyces lilacinus

Elbandy¹,

Shinde²,

Hong³

et al. 2009

Bulletin of the Korean Chemical Society

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New α-pyrones (1 and 2) and cyclohexenones (13 and 14) were isolated along with known analogues (3, 5−12) from the ethyl acetate extract of the whole broth of the fungus Paecilomyces lilacinus, a strain derived from a marine sponge Petrosia sp. Their structures were established by interpretation of 1D and 2D NMR, and FABMS data. It is interesting to isolate cyclohexenone derivatives from the genus Paecilomyces (family Trichocomaceae, order Eurotiales), since these cyclohexenones were previously reported only from far distinct genera, Phoma and Alternaria (family Pleosporaceae, order Pleosporales). Compounds 6, 7, and 9 were evaluated for cytotoxicity against a small panel of human solid tumor cell lines. Their cytotoxicity was insignificant upto a concentration of 30 µg/mL.

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Section: Resultsmentioning

confidence: 99%

α-Pyrones and Yellow Pigments from the Sponge-Derived Fungus Paecilomyces lilacinus

Elbandy¹,

Shinde²,

Hong³

et al. 2009

Bulletin of the Korean Chemical Society

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“…However, infectopyrones have been found in other genera, such as Phoma Sacc., Stemphylium Wallr. and Ulocladium Preuss (Pedras and Chumala, 2005;Christensen et al, 2005;Andersen and Hollensted, 2008, respectively).…”

Section: Introductionmentioning

confidence: 99%

A polyphasic approach to the taxonomy of the Alternaria infectoria species–group

Andersen

Sørensen

Nielsen

et al. 2009

Fungal Genetics and Biology

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“…2 Surprisingly, the biosynthesis experiments proved two different pathways: a mixed acetate/propionate in Streptomyces 3 and methylation of a polyacetate chain in fungi. 4,5 Related compounds were found in some marine organisms and, in particular, in sacoglossan molluscs. 6 Origin and function of these molecules are challenging topics for international debates.…”

Section: A-pyrone Polypropionatesmentioning

confidence: 99%

Aplysiopsenes: an additional example of marine polyketides with a mixed acetate/propionate pathway

Ciavatta¹,

Manzo²,

Nuzzo³

et al. 2009

Tetrahedron Letters

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Phomapyrones from blackleg causing phytopathogenic fungi: isolation, structure determination, biosyntheses and biological activity

Cited by 41 publications

References 16 publications

α-Pyrones and Yellow Pigments from the Sponge-Derived Fungus Paecilomyces lilacinus

α-Pyrones and Yellow Pigments from the Sponge-Derived Fungus Paecilomyces lilacinus

A polyphasic approach to the taxonomy of the Alternaria infectoria species–group

Aplysiopsenes: an additional example of marine polyketides with a mixed acetate/propionate pathway

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