Phosphorofluoridic Acid as an Efficient Catalyst for One Pot Synthesis of Dihydropyrimidinones under Solvent Free and Ambient Condition

Mathapati, Sushil R.; Prasad, Divya; Atar, Amol B.; Nagaraja, Bhari Mallanna; Dawle, Jairaj K.; Patil, Komal

doi:10.1016/j.matpr.2018.10.390

Cited by 14 publications

(2 citation statements)

References 28 publications

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“…Metal-free heterocatalytic synthetic routes are preferred to minimize heavy metal waste and allow the reuse of the catalyst to reduce the environmental footprint. N-Heterocyclic compounds were also synthesized using a metal-free catalyst such as dicationic room temperature ionic liquids, 18 fluorophosphoric acid, 19 phosphorofluoridic acid 20 and zinc sulfamate. 21 Exploration of carbonaceous materials has gathered tremendous attention as a metal-free catalyst owing to their superior physicochemical properties of being cost-effective, recyclable, and environmentally friendly.…”

Section: Introductionmentioning

confidence: 99%

Improving the yield of graphene oxide-catalysed N-heterocyclization of amines through fed batch mode

2022

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Section: Introductionmentioning

confidence: 99%

Improving the yield of graphene oxide-catalysed N-heterocyclization of amines through fed batch mode

2022

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“…Among these, the most inspected nano-scale metal oxides is tin dioxide (SnO 2 ), due to its physical and chemical properties which major contributed for different application aspects. As an effort to enhance the electronic property and to improve surface area, SnO 2 can be incorporated on MWCNTs to form a composite material and can be used as a catalyst for organic transformation with the help of improved active sites on the surface [49][50][51][52][53][54]. Such attractive physicochemical properties of SnO 2 @MWCNTs as nano composite prompted us to study its catalytic e ciency in quinoxalines synthesis.…”

Section: Introductionmentioning

confidence: 99%

Tailored SnO2@MWCNTs efficient and recyclable nano-catalyst for selective synthesis of 4, 5-dihydropyrrolo [1, 2-a] quinoxalines via Pictet–Spengler reaction

et al. 2022

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Heterocyclic compounds have wide range of applications and Pictet-Spengler reaction is effectual in the synthesis of heterocyclic compounds such as quinoline and isoquinoline. The present work describes an effective Pictet-Spengler-type protocol for the selective synthesis of quinoxaline derivatives from substituted pyrroles and diverse aromatic aldehydes over tailored SnO 2 nanoparticles anchored multi walled carbon nanotubes (SnO 2 @MWCNTs) nano-catalyst under greener reaction condition. An elementary reaction process (chemical synthesis) of oxidation of MWCNTs followed by uniform dispersion of SnO 2 nanoparticles is used to synthesize the SnO 2 @MWCNTs catalyst. The SnO 2 @MWCNTs catalyst was then characterized by using modern spectroscopic and analytical techniques. The activity of catalysts was investigated towards the formation of selective quinoxaline. The reaction progressed with 100% conversion and 93 − 80% yield for the desired product at ambient operating conditions in just 2.30-3.30 h of reaction time. The effect of different parameters such as reaction temperature, time, and loading of SnO 2 on MWCNTs, SnO 2 @MWCNTs catalyst loading were also investigated and discussed in detail. The protocol displayed high tolerance to different functionalities with respect to different substituted aromatic aldehydes to form quinoxaline derivatives in e cient and selective yield. Plausible reaction mechanistic pathway for the selective formation of quinoxaline over SnO 2 @MWCNTs is also proposed. It is believed that, high dispersion of SnO 2 over MWCNTs provided su cient Lewis acidic sites for the reaction to selectively obtain the nal product. Additionally, recyclability of SnO 2 @MWCNTs catalyst was also studied which demonstrated that the catalyst could be e ciently reused for six successive cycles without signi cant loss of activity and selectivity. The present work provides greener approach for synthesis of quinoxaline derivative preparation with high selectivity (free from oxidized quinoxaline as a side-product) and e cient yield.

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Agar Supported NiO NPs: A Sustainable Approach for synthesis of 3,4‑dihydropyrimidin‑2 (1H)‑Ones in Aqueous Hydrotropic Media

Attar¹,

Sapkal²,

Dhane³

et al. 2023

Catal Lett

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Phosphorofluoridic Acid as an Efficient Catalyst for One Pot Synthesis of Dihydropyrimidinones under Solvent Free and Ambient Condition

Cited by 14 publications

References 28 publications

Improving the yield of graphene oxide-catalysed N-heterocyclization of amines through fed batch mode

Improving the yield of graphene oxide-catalysed N-heterocyclization of amines through fed batch mode

Tailored SnO2@MWCNTs efficient and recyclable nano-catalyst for selective synthesis of 4, 5-dihydropyrrolo [1, 2-a] quinoxalines via Pictet–Spengler reaction

Agar Supported NiO NPs: A Sustainable Approach for synthesis of 3,4‑dihydropyrimidin‑2 (1H)‑Ones in Aqueous Hydrotropic Media

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