Background: The relationship between the sizes of the structures that form our face, such as lips, philtrum, and the jaw, and our personality characteristics are unknown. In this study, it was scientifically researched whether lip, jaw and philtrum anatomy can give us clues on personality characteristics or not.Methods: The photographs of the university students were taken using digital camera in two positions. The students who were photographed were asked to simultaneously complete personality test. The photographs were transferred to the computer and, using photoshop program installed on the computer, measurements were made. The mouth widths, upper and lower lip thicknesses, the distance between lip spots, philtrum length and width, lateral mouth width, jaw heights were recorded, and lip type and philtrum depth were identified. The results were compared to the personality characteristics of the students.Results: Lip thicknesses were found to be correlated positively only with the ‘openness to experience’ trait from among personality characteristics. A positive correlation between lip type and ‘conscientiousness’ was also found. There was a negative correlation between philtrum length and ‘negative valence’.Conclusions: This study shows that lip thickness and philtrum length can give us an idea regarding personality characteristics.