Photoanode-supported cathodic immunosensor for sensitive and specific detection of human chorionic gonadotropin

Lu, Yibin; Wang, Hao; Shi, Xiaomei; Ding, Caifeng; Fan, Gao-Chao

doi:10.1016/j.aca.2022.339560

Cited by 8 publications

(5 citation statements)

References 49 publications

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“…However, the photocurrent intensity reached only 0.26 μA, which was attributed to its poor visible light absorption and fast electron–hole recombination, as well as the sluggish transfer kinetics of the charge carriers with the surrounding media. 21 After immersion of the TiO 2 NP electrode into a mixed solution of Tyr and l -ty, the photocurrent promptly increased to 1.18 μA, with an increment of 3.5 times the intensity before reaction (curve b in Fig. 1C).…”

Section: Resultsmentioning

confidence: 96%

See 1 more Smart Citation

Facile and sensitive photoelectrochemical detection of kojic acid in food products: a general strategy for immobilization-free analysis of enzyme inhibitors

Zhang

Zhu

et al. 2022

Analyst

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Section: Resultsmentioning

confidence: 96%

“…Among diverse materials, TiO 2 has garnered enormous attention because of its nontoxicity, high photostability and environmentally friendly nature. 21 In this work, a TiO 2 NP photoelectrode was prepared simply on a bare FTO slide via an LPD process and annealing at 500 °C. Its microstructure and PEC performance are depicted in Fig.…”

Section: Resultsmentioning

confidence: 99%

Facile and sensitive photoelectrochemical detection of kojic acid in food products: a general strategy for immobilization-free analysis of enzyme inhibitors

Zhang

Zhu

et al. 2022

Analyst

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“…Biomolecular assays for proteins, peptides, and nucleic acids have played a key role in diagnosis and early detection. A broad range of methods have been reported, including strip-type (pregnancy test, [1][2][3][4][5][6] COVID-19 test [7][8][9] ), electrochemical sensing (field effect transistor type, [10][11][12][13] blood glucose sensor-type [14][15][16][17] ), and fluorescence type, [18][19][20][21][22] among others. Researchers have focused on increasing the sensitivity of these technologies for the early DOI: 10.1002/macp.202300382 detection of possible harmful substances, such as viruses and biological warfare agents.…”

Section: Introductionmentioning

confidence: 99%

Enhancement of Sensitivity for Retroreflection‐Based Biosensor by Controlling Polymer Brush on Janus Particles

Xu,

Choi,

Yoo

et al. 2024

Macro Chemistry & Physics

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Among the methods for onsite detection of specific biomolecules, the use of retroreflective Janus particles (RJPs) is a simple and efficient method for biophotonic probes to detect biotarget molecules with spatioselectivity, which can make the RJPs align toward light sources after capturing the target biomolecules, enhancing retroreflection. Because RJP has two distinct regions with different properties, specific reagents can be easily functionalized through chemical reactions between the functional groups and biotarget molecules. The number of functional groups on RJP will be the critical parameter for efficiency of sensing ability. Here, we introduce clickable (azide) polymer brush on surface of RJP via different surface polymerization methods (grafting to and grafting from method). Azide groups allow for the easy modification of dibenzocyclooctyne‐linked biomolecules onto silica particles through click chemistry. We prepare RJPs with different quantities of azide functional groups on their surfaces via solvent volatilization method and metal deposition. Using a retroreflective immunosensing system, we perform sensitive detection of target biomolecules.This article is protected by copyright. All rights reserved

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“…Firstly, a more stringent testing environment is required. Secondly, its stability and photoelectric conversion efficiency need to be improved [ 25 ]. Therefore, PEC immunosensors not only need bioactive materials with high photoelectric conversion efficiency, a large absorption range, and good stability, but also need to increase the diversity of the detection environment and the tolerance of the sensors [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

Ultrasensitive Photoelectrochemical Immunoassay Strategy Based on Bi2S3/Ag2S for the Detection of the Inflammation Marker Procalcitonin

Zhao

Wang

et al. 2023

Biosensors

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As an inflammatory marker, procalcitonin (PCT) is more representative than other traditional inflammatory markers. In this work, a highly efficient photoelectrochemical (PEC) immunosensor was constructed based on the photoactive material Bi2S3/Ag2S to realize the sensitive detection of PCT. Bi2S3 was prepared by a hydrothermal method, and Ag2S quantum dots were deposited on the ITO/Bi2S3 surface via in situ reduction. Bi2S3 is a kind of admirable photoelectric semiconductor nanomaterial on account of its moderate bandgap width and low binding rate of photogenerated electron holes, which can effectively convert light energy into electrical energy. Therefore, based on the energy level matching principle of Bi2S3 and Ag2S, a labeled Bi2S3/Ag2S PEC immunosensor was constructed, and the sensitive detection of PCT was successfully established. The linear detection range of the PEC immunosensor was 0.50 pg∙mL−1 to 50 ng∙mL−1, and the minimum detection limit was 0.18 pg∙mL−1. Compared with the traditional PEC strategy, the proposed PEC immunosensor is simple, convenient, and has good anti-interference, sensitivity, and specificity, which could provide a meaningful theoretical basis and reference value for the clinical detection of PCT.

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Photoanode-supported cathodic immunosensor for sensitive and specific detection of human chorionic gonadotropin

Cited by 8 publications

References 49 publications

Facile and sensitive photoelectrochemical detection of kojic acid in food products: a general strategy for immobilization-free analysis of enzyme inhibitors

Facile and sensitive photoelectrochemical detection of kojic acid in food products: a general strategy for immobilization-free analysis of enzyme inhibitors

Enhancement of Sensitivity for Retroreflection‐Based Biosensor by Controlling Polymer Brush on Janus Particles

Ultrasensitive Photoelectrochemical Immunoassay Strategy Based on Bi2S3/Ag2S for the Detection of the Inflammation Marker Procalcitonin

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