Photodynamic Therapy in Veterinary Medicine: From Basics to Clinical Practice

Abstract

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Terapia Fotodinâmica: Conceitos básicos e aplicações veterinárias

“…A Terapia Fotodinâmica (TFD) é uma técnica bem menos invasiva do que a grande maioria dos procedimentos convencionais para o tratamento de doenças como o câncer. Desde que o órgão ou tecido biológico seja acessível à incidência de luz (a partir de uma fonte que pode ser propiciada a partir de diferentes aparatos), a TFD pode ser uma interessante alternativa para os procedimentos clínicos veterinários em várias enfermidades (Sellera et al, 2016). O fato de ser menos invasiva e de proporcionar menos mal-estar aos pacientes antes, durante e após as aplicações, gerando, inclusive, menos sequelas, torna a TFD uma alternativa a ser considerada pelos clínicos.…”

Equine Sarcoid

“…The mechanism is complex and takes advantage of the production of reactive oxygen species that kill sensitized cells, so it is very localized. The literature on its use on sarcoids is limited but significant benefits are reported, with or without surgical debulking [3,[84][85][86][87][88].…”

Photodynamic Therapy in Veterinary Medicine: Applications in dogs and cats

“…Despite Photodynamic Therapy (PDT) is a well-stablished therapeutic methodology in human medicine, its application in veterinary medicine remains less common (Buchholz & Walt, 2013). However, the ease of use, anti-resistance capability, and excellent cosmetic outcomes should be arguments to a higher application of PDT in animal healthcare (Sellera et al, 2016).…”

“…Other indications have been made to neoplasia in urinary tract of dogs and sarcoid equines (Buchholz & Walt, 2013). Novel perspectives for PDT application in veterinary medicine have been proposed and tested in different types of cancer and microbial infectious diseases (Sellera et al, 2016).…”