Photonic crystal based biosensor for the detection of glucose concentration in urine

Robinson, S.; Dhanlaksmi, Nagaraj

doi:10.1007/s13320-016-0347-3

Cited by 109 publications

(28 citation statements)

References 32 publications

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“…In recent years, the use of photonic nano-sensors as bio-sensors is a hot topic of research, with a plethora of designs and applications [18][19][20][21][22][23]. Therefore, in the following, the behavior of the system described in the previous section as biosensor is considered.…”

Section: Study Of the Bio-sensing Properties Of The Systemmentioning

confidence: 99%

A study on refractive index sensors based on optical micro-ring resonators

Tsigaridas

2017

Photonic Sens

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Abstract:In this work, the behavior of refractive index sensors based on optical micro-ring resonators is studied in detail. Using a result of waveguide perturbation theory in combination with numerical simulations, the optimum design parameters of the system, maximizing the sensitivity of the sensor, are determined. It is found that, when optimally designed, the sensor can detect relative refractive index changes of the order of n/n310 4 , assuming that the experimental setup can detect relative wavelength shifts of the order of /310 5. The behavior of the system as bio-sensor has also been examined. It is found that, when optimally designed, the system can detect refractive index changes of the order of n10 3 for a layer thickness of t=10 nm, and changes in the layer thickness of the order of t0.24 nm, for a refractive index change of n=0.05.

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Section: Study Of the Bio-sensing Properties Of The Systemmentioning

confidence: 99%

A study on refractive index sensors based on optical micro-ring resonators

Tsigaridas

2017

Photonic Sens

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“…Researchers aim to develop more technological tools to investigate the glucose concentration in alternative biofluids and examine the correlation of such glucose levels with blood glucose level [69,70]. Concentration ranges of glucose in alternative fluids are around 0.006-2 mM (sweat) [71][72][73], 3.9-6.6 (interstitial fluid) [74], 2.78-5.56 mM (urine) [75,76], and 0.03-1.39 mM (saliva) [64,65,77,78]. The use of nanomaterials is important to help the sensor to be able to operate under fluctuating conditions of real biological systems.…”

Section: Developing Glucose Sensorsmentioning

confidence: 99%

Applying Nanomaterials to Modern Biomedical Electrochemical Detection of Metabolites, Electrolytes, and Pathogens

2020

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Personal biosensors and bioelectronics have been demonstrated for use in out-of-clinic biomedical devices. Such modern devices have the potential to transform traditional clinical analysis into a new approach, allowing patients or users to screen their own health or warning of diseases. Researchers aim to explore the opportunities of easy-to-wear and easy-to-carry sensors that would empower users to detect biomarkers, electrolytes, or pathogens at home in a rapid and easy way. This mobility would open the door for early diagnosis and personalized healthcare management to a wide audience. In this review, we focus on the recent progress made in modern electrochemical sensors, which holds promising potential to support point-of-care technologies. Key original research articles covered in this review are mainly experimental reports published from 2018 to 2020. Strategies for the detection of metabolites, ions, and viruses are updated in this article. The relevant challenges and opportunities of applying nanomaterials to support the fabrication of new electrochemical biosensors are also discussed. Finally, perspectives regarding potential benefits and current challenges of the technology are included. The growing area of personal biosensors is expected to push their application closer to a new phase of biomedical advancement.

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“…Biosensing applications are vital in the photonics research community, where a vast number of biosensors were developed using different platforms such as the silicon nanowire biosensors [9], plasmonic biosensors [24], and photonic crystal biosensors [25].…”

Section: Biosensing Applicationsmentioning

confidence: 99%

Vertical silicon nanowire-based racetrack resonator optical sensor

et al. 2019

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We propose a highly sensitive optical sensor which is built from silicon nanowires. The silicon nanowires are arranged to form a ring resonator. The silicon nanowires cladding and voids are filled with the analyte. The sensor has a small footprint of 16 μm × 16.5 μm. The insertion loss of the sensor is only 0.4 dB, while it is characterized by its high sensitivity of 430 nm/ RIU. As a biosensor, our device showed a 100 nm/RIU sensitivity when a thin biolayer of 10 nm thickness is attached to the silicon nanowire structures.

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Photonic crystal based biosensor for the detection of glucose concentration in urine

Cited by 109 publications

References 32 publications

A study on refractive index sensors based on optical micro-ring resonators

A study on refractive index sensors based on optical micro-ring resonators

Applying Nanomaterials to Modern Biomedical Electrochemical Detection of Metabolites, Electrolytes, and Pathogens

Vertical silicon nanowire-based racetrack resonator optical sensor

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