Photosensitivity induced by paroxetine

Vilaplana, J.; Botey, E.; Lecha, M; Herrero, C; Romaguera, C.

doi:10.1034/j.1600-0536.2002.470210_10.x

Cited by 11 publications

(4 citation statements)

References 7 publications

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“…The responsible drugs were paroxetine in three cases and fluvoxamine in two. In three cases, a positive reaction was observed only in the area irradiated with UVA (3, 4). In the other two patients, the positive photopatch test was observed with both UVB and UVA (2) or, as in our patient, only in the area irradiated with UVB (4).…”

Section: Discussionmentioning

confidence: 99%

“…Cutaneous adverse drug reactions due to ISSRs are rare, but may include severe skin disorders, such as the Stevens–Jonhson syndrome, acute generalized exanthematous pustulosis and toxic epidermal necrolysis. Photosensitivity reactions due to SSRIs are infrequent (2, 3, 4). To our knowledge, PEM induced by SSRIs has not been described previously.…”

Section: Discussionmentioning

confidence: 99%

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Erythema multiforme photoinduced by paroxetine and herpes simplex virus

Rodríguez-Pazos

Gómez-Bernal

Montero

et al. 2011

Photoderm Photoimm Photomed

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Erythema multiforme (EM) is a self-limited skin disease, characterized by the abrupt onset of symmetric red papules that may evolve into target lesions often precipitated by an infection. Photosensitive erythema multiforme (PEM) is a rare disorder characterized by the distribution of the lesions on sun-exposed areas. It has been described at the sites of sunburn, following episodes of polymorphic light eruption or herpes labialis and in association with drugs. To our knowledge, PEM photoinduced by selective serotonin reuptake inhibitors has not been reported. We describe a patient who had two consecutive episodes of PEM related to two different triggers: paroxetine and HSV infection. In the first episode, systemic photosensitivity was confirmed with the photobiological study. UVB-MED was decreased when the patient was taking paroxetine and did not change after its substitution for duloxetine. However, it became normal after the withdrawal of both drugs, suggesting a cross-reactivity reaction. The UVB photopatch test with paroxetine was positive. The second episode occurred after a herpes labialis relapse. At that time, UVB-MED was normal.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Erythema multiforme photoinduced by paroxetine and herpes simplex virus

Rodríguez-Pazos

Gómez-Bernal

Montero

et al. 2011

Photoderm Photoimm Photomed

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“…Eight cases of photoreactions induced by other SSRI have been reported and are detailed in Table 1. In cases 1 (paroxetine), 3 (fluvoxamine), 5 (fluoxetin) and 8 (citalopram), the suggested mechanism was phototoxicity because of the clinical aspect 3–6 . In cases 2, 4 and 7, photoallergy is suspected 7–9 .…”

Section: Photosensitivity Cases Induced By Ssrimentioning

confidence: 99%

Escitalopram photo‐induced erythroderma

Ram-Wolf

Mahé

Saïag

2008

Acad Dermatol Venereol

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In parallel, the level of pruritus self-assessed by the subjects showed a stronger and higher decrease (73.4%) in the 5% LRP-biomass lotion treated group at day 28 vs. 49.4% decrease (t-test, P = 0.01) in vehicle-treated group ( fig. 2).Moreover, the total clinical score remained almost unchanged in the test lotion-treated group 1 week after daily treatment was stopped.Overall, this study showed that LRP-biomass lotion was effective in improving SD symptoms and may be valuable when used between conventional drug treatments. It may suggest that this LRP-biomass has tolerogenic effect and may also modulate the defensins synthesis that may participate to the efficacy by decreasing scalp microflora dysregulation. More generally, the active LRP-biomass used at lower concentration may be beneficial to reduce scalp scaling when incorporated into a dandruff shampoo.

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“…3,14 Photodermatitis or urticaria limited to photoexposed areas, occurring mainly on the face, neck, the backs of the hands, and shoulders, has also been described. [33][34][35][36] Acute generalized exanthematous pustulosis with a photodistribution pattern induced by sertraline has been noted as well. 24 DYSCHROMIA Treatment using SSRIs lasting many years may result in cutaneous hyperpigmentation of skin, hair, and nails.…”

Section: Flare Of Psoriasis Vulgarismentioning

confidence: 99%