Phthalates in dormitory dust and human urine: A study of exposure characteristics and risk assessments of university students

Hua, Liting; Guo, Sai; Jing, Xu; Yang, Xiaomeng; Zhu, Hongkai; Yao, Yiming; Zhu, Lin; Li, Yongcheng; Zhang, Jingran; Sun, Hongwen; Zhao, Hongzhi

doi:10.1016/j.scitotenv.2022.157251

Cited by 24 publications

(6 citation statements)

References 69 publications

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“…Investigations into the sources of primary plasticizers have mainly focused on 'usual suspect' sources that are already regulated, including food-contact materials, toys and childcare items, personal care products, and medical devices [18][19][20][21][22][23][24][25][26][27] . Reports on additional indoor sources of primary plasticizers are emerging [98][99][100] , such as the work by Promtes et al, who attributed elevated levels of DEHP and DINP in dust collected from Thai homes to PVC flooring materials and other 'usual suspect' objects [101] . The prevalence of these two PAEs were mirrored by our results, as well as other reports [24] .…”

Section: Discussionmentioning

confidence: 99%

Ecological and health risks of polycyclic aromatic hydrocarbons in the sediment core of Phayao Lake, Thailand

Deelaman¹,

Choochuay²,

Pongpiachan³

et al. 2023

J Environ Expo Assess

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Polycyclic aromatic hydrocarbons (PAHs) in sediment cores from Phayao Lake were investigated in terms of their concentration, distribution, and potential effects on the environment and human health. The concentration of Σ16PAHs ranged from 77.6 to 1251.1 ng g-1. Additionally, low molecular weight PAHs (two or three fused aromatic rings) were dominant, indicating that the main source of PAHs is the incomplete combustion of organic sources. The toxic equivalent quantities (TEQs) of 16 PAHs varied from 2.67 to 155.09 ng g-1, with an average of 38.29 ± 46.69 ng g-1. Furthermore, the TEQs of 9 known carcinogenic PAHs averaged 20.77 ± 30.63 ng g-1. B[a]P had the highest TEQ, followed by D[a,h]A and B[k]F, with values of 16.93 ± 25.49, 13.89 ± 15.37 and 2.12 ± 3.64, respectively. The RQ(NCs) of ∑PAHs (RQ∑PAHs(NCs)) ranged from 1.65 × 10-4 to 6.27 × 10-1 with an average value of 1.18 × 100 ± 1.52 × 100. Moreover, RQ(NCs) was less than 1 for individual PAHs, indicating a minor risk. However, RQ(MPCs) was less than 1 for individual PAHs, indicating a moderate risk. The results showed a significant incremental lifetime cancer risk (ILCR) from sediment-bound PAHs with dermal absorption, followed by ingestion and inhalation, as the prevalent route of exposure. The measured ILCR values of all PAHs were less than 10-6 for both adults and children, which were lower than the baseline value, indicating that each PAH poses a low risk of cancer to humans. This study provides information for control and preventive actions to limit future PAH pollution in Phayao Lake.

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Section: Discussionmentioning

confidence: 99%

Ecological and health risks of polycyclic aromatic hydrocarbons in the sediment core of Phayao Lake, Thailand

Deelaman¹,

Choochuay²,

Pongpiachan³

et al. 2023

J Environ Expo Assess

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“…The mass spectrometer was operated in multiple reaction monitoring and negative ion mode. The mobile phase gradient elution procedure and the optimized mass spectrum parameters were detailed in our previous study …”

Section: Methodsmentioning

confidence: 99%

“…The recoveries of mPAEs in urine samples ranged from 85.60% to 114.00% (25.00 ng mL –1 ). Detailed information on the recovery and limit of detection (LOD) can be found in our previous study …”

Section: Methodsmentioning

confidence: 99%

“…The mobile phase gradient elution procedure and the optimized mass spectrum parameters were detailed in our previous study. 29…”

Section: Sample Preparation and Lc−ms/ms Analysismentioning

confidence: 99%

“…Detailed information on the recovery and limit of detection (LOD) can be found in our previous study. 29…”

Section: Quality Assurance and Quality Controlmentioning

confidence: 99%

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Current Phthalate Exposure Risks of Rural Population in the Northwest China: Evidence from an Internal Exposure Study

Zheng,

Hua,

Zhang

et al. 2024

Environ. Health

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Phthalates (PAEs) are synthetic chemicals widely used in industrial and personal consumer products as adhesives or plasticizers. PAEs have been demonstrated to have toxic effects on the human body. However, biological monitoring data for the internal PAE exposure levels of Chinese rural residents are still limited. The present study investigated the exposure levels of ten phthalate metabolites (mPAEs) of rural residents in Northwest China. The results showed that mPAEs were wildly prevalent in urine and the geometric mean concentration of Σ10mPAEs was 957.02 ng mL–1 (adjusted by specific gravity). Mono-n-butyl phthalate (MBP) and metabolites of di(2-ethylhexyl)-phthalate (DEHP) were the most dominant mPAEs in urine, with specific gravity adjusted median concentrations of 174.67 and 156.30 ng mL–1, respectively. Urinary concentrations of mPAEs were significantly associated with age, body mass index and economic level (p < 0.05). By calculating the percentage and relative conversion rate of DEHP metabolites, it was found that the degree of oxidative metabolism of DEHP in children was significantly higher than that in adults (p < 0.05), indicating that the pathway and degree of DEHP oxidation were age-related. The risk assessment showed that 59.12% of rural residents may have a noncancer risk from PAE exposure. This study provides important basis for assessing the occurrence and exposure of urinary phthalate metabolites among rural residents in China.

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Liquid crystal monomers (LCMs) in indoor residential dust from Beijing, China: occurrence and human exposure

Li,

Lyu,

et al. 2024

Environ Sci Pollut Res

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Phthalates in dormitory dust and human urine: A study of exposure characteristics and risk assessments of university students

Cited by 24 publications

References 69 publications

Ecological and health risks of polycyclic aromatic hydrocarbons in the sediment core of Phayao Lake, Thailand

Ecological and health risks of polycyclic aromatic hydrocarbons in the sediment core of Phayao Lake, Thailand

Current Phthalate Exposure Risks of Rural Population in the Northwest China: Evidence from an Internal Exposure Study

Liquid crystal monomers (LCMs) in indoor residential dust from Beijing, China: occurrence and human exposure

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