IOC Manual of Sports Cardiology 2016
DOI: 10.1002/9781119046899.ch6
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Physical Activity in the Prevention and Management of Atherosclerotic Disease

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“…Ñ÷èòàåòñÿ, ÷òî ÀÄÏAE ÿâëÿåòñÿ âðîaeäåííûì çàáîëåâàíèåì ìèîêàðäà àóòîñîìíî-äîìèíàíòíîãî òèïà, âûçâàííûì ìóòàöèåé ãåíîâ, êîäèðóþùèõ äåñìîñîìíûå áåëêè, ÷òî ïðèâîäèò ê ôîðìèðîâàíèþ â ìèîêàðäå ïðîíèêàþùèõ î÷àãîâ ïîðàaeåíèÿ ñ ðàçíîé ñòåïåíüþ âûðàaeåííîñòè [39,40,41]. Ãåíåòè÷åñêàÿ ïðèðîäà çàáîëåâàíèÿ ïîêà ïîëíîñòüþ íå äîêàçàíà, õîòÿ óaeå êàðòèðîâàíû ñåìü ó÷àñòêîâ ÷åòûðåõ [1,3,10,14] õðîìîñîì [42). Ýòè ó÷àñòêè ãåíà, îáóñëîâëèâàþùèå çàáîëåâàíèå, àññîöèèðóþòñÿ ñ äåñìîñîìíûìè áåëêàìè, âêëþ÷àÿ ïëàêîãëîáèí, äåñìîïëàêèí, ïëàêîôèëèí è äåñìîãëåèí [43].…”
Section: àðèòìîãåííàÿ äèñïëàçèÿ ïðàâîãî Aeåëóäî÷êà ñåðäöàunclassified
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“…Ñ÷èòàåòñÿ, ÷òî ÀÄÏAE ÿâëÿåòñÿ âðîaeäåííûì çàáîëåâàíèåì ìèîêàðäà àóòîñîìíî-äîìèíàíòíîãî òèïà, âûçâàííûì ìóòàöèåé ãåíîâ, êîäèðóþùèõ äåñìîñîìíûå áåëêè, ÷òî ïðèâîäèò ê ôîðìèðîâàíèþ â ìèîêàðäå ïðîíèêàþùèõ î÷àãîâ ïîðàaeåíèÿ ñ ðàçíîé ñòåïåíüþ âûðàaeåííîñòè [39,40,41]. Ãåíåòè÷åñêàÿ ïðèðîäà çàáîëåâàíèÿ ïîêà ïîëíîñòüþ íå äîêàçàíà, õîòÿ óaeå êàðòèðîâàíû ñåìü ó÷àñòêîâ ÷åòûðåõ [1,3,10,14] õðîìîñîì [42). Ýòè ó÷àñòêè ãåíà, îáóñëîâëèâàþùèå çàáîëåâàíèå, àññîöèèðóþòñÿ ñ äåñìîñîìíûìè áåëêàìè, âêëþ÷àÿ ïëàêîãëîáèí, äåñìîïëàêèí, ïëàêîôèëèí è äåñìîãëåèí [43].…”
Section: àðèòìîãåííàÿ äèñïëàçèÿ ïðàâîãî Aeåëóäî÷êà ñåðäöàunclassified
“…Ïðîôèëàêòèêà ÈÁÑ ó ñïîðòñìåíîâ çàêëþ÷àåòñÿ â íîðìàëèçàöèè ìàññû òåëà, ñíèaeåíèè óâåëè÷åííîãî ïðîöåíòà aeèðîâîé òêàíè â îðãàíèçìå, óñòðàíåíèè äèñëèïèäåìèè (íîðìàëèçàöèÿ óðîâíÿ îáùåãî õîëåñòåðèíà, òðèãëèöåðèäîâ è õîëåñòåðèíà íèçêîé ïëîòíîñòè), ñíèaeåíèè ïîâûøåííîãî àðòåðèàëüíîãî äàâëåíèÿ, îðãàíèçàöèè ñáàëàíñèðîâàííîãî òðåíè-ðîâî÷íîãî ïðîöåññà ñ îïòèìàëüíûì ïðîöåíòîì àýðîáíîé íàãðóçêè íèçêîé è ñðåäíåé èíòåíñèâíîñòè, óìåíüøåíèè ñòðåññîâûõ âîçäåéñòâèé â áûòó, íà òðåíèðîâêàõ è ñîðåâíîâàíèÿõ [1,3,59].…”
Section: äèëàòàöèîííàÿ êàðäèîìèîïàòèÿunclassified
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