Physical Therapy Alone Compared with Core Decompression and Physical Therapy for Femoral Head Osteonecrosis in Sickle Cell Disease

Abstract

In this randomized prospective study, physical therapy alone appeared to be as effective as hip core decompression followed by physical therapy in improving hip function and postponing the need for additional surgical intervention at a mean of three years after treatment.

Treatment of Femoral Head Osteonecrosis in the United States: 16-year Analysis of the Nationwide Inpatient Sample

“…Treatment options have continued to evolve for osteonecrosis and include potential nonoperative pharmacotherapies (such as anticoagulants, bisphosphonates, shockwave therapy, or hyperbaric oxygen) [5,6,16,17,23,24,43,52,68]; joint-preserving surgeries (core decompression and various vascularized and nonvascularized bone grafting procedures) [18,35,36]; and joint-replacing surgeries, including THA. Although numerous treatment algorithms have been proposed to provide guidance to the treating physician [18,19,45,58,64], controversy remains surrounding the most appropriate surgery and at what stage of the disease process these procedures should be performed [9,10,34,50,59,60].…”

Rehabilitation Program after Cell Therapy for Treatment of Femoral Head Osteonecrosis: A Narrative Review of Literature

“…Yamaguchi et al reported that treadmill running after transplantation of bone marrow-derived MSCs can promote cartilage regeneration [39]. Some mechanical stimulations, such as ultrasound and gravity force, also promote cell differentiation and proliferation [41,42]. Biomechanical, biophysical, physiological, and radiological knowledge are essential in designing the protocol for musculoskeletal rehabilitation.…”

“…Biomechanical, biophysical, physiological, and radiological knowledge are essential in designing the protocol for musculoskeletal rehabilitation. However, treatment programs for ONFH without cell therapy have not been improved since the report of Neumayr et al [42]. Developing a rehabilitation program is important.…”

Musculoskeletal complications in sickle cell anemia patients: a ten-year retrospective review of hospital-based records (1991-2000) in two Nigerian hospitals

“…Even though Physiotherapy has been seen to improve and efficiently treat musculoskeletal dysfunctions in SCA patients. 3,31 According to 32 majority of sickle cell patients managed with chemotherapy alone were seen as very unstable, hence, the recent development and treatment concepts advocate combination of several types of therapies other than chemotherapy alone, especially as regards joints pain and pain crisis. Therefore management of SCA requires holistic interdisciplinary evidence-based approaches.…”