Physicochemical, optical and electrical investigation on poly [(phenylene-2-one)-co-(thiophene)] novel soluble conductive polymer as-synthesized through heterogeneous catalysis route

Biorelevant Weakly Coordinating Directing Group Assisted C–H Alkenylation with Cyclopropanols via Sequential C–H/C–C Activation

“…Implementation of this method toward material sciences and drug discovery has attracted tremendous attention within the scientific community in recent years . Since the discovery of penicillin by Fleming, β-lactams are the most prevalent building block of antibiotics while γ-lactam derivatives represent an important structural scaffold of numerous pharmaceuticals such as α v β 3 -antagonists and brivaracetam drugs (Scheme A). , In addition, the isoindolinone, morpholinone and pyridone classes of heterocycles are prevalent as one of the fundamental functionalities in plentiful natural products and pharmacophores. , Moreover, ε-caprolactam has irrebuttable significance in industrial chemistry with diverse activities viz. synthesis of nylon, paint and plastic .…”

“…In this paradigm, utilization of these readily available bioactive molecules as intrinsic weakly coordinating directing groups (DGs) for the regioselective C–H bond functionalization would be a linchpin tool for rapid construction of value-added complex organic molecular scaffolds. Furthermore, the functionalization of N -arylated derivatives of the aforementioned molecules has attracted considerable attention as they are intimately woven into alkaloids and drug candidates . In addition, α,β-unsaturated ketones are the quintessential functional handle in organic synthesis; the development of a new avenue for their introduction would thus be useful.…”