Physicochemical properties and in vitro stability studies  of green synthesized gold nanoparticles using  pelargonium sidoides

Badeggi, Umar Muhammad; Lawal, B.A.; Akinfenwa, A.O.; Ayipo, Y.O.; Azeh, Yakubu; Dagaci, M.Z.

doi:10.4314/njt.v39i3.18

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…There are few reports that address an analysis of the stability of functionality or conservation of initial characteristics of the NPs synthesized by a green pathway [110][111][112]. In most of the reported works, a robust approach is made towards the synthesis methods, the characterization of the NPs synthesized with plant extracts, and their potential applications.…”

Section: Relationship Of the Synthesis Process Variables And Cunp Pro...mentioning

confidence: 99%

Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications

Antonio-Pérez,

Durán-Armenta,

Pérez-Loredo

et al. 2023

Micromachines

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Copper nanoparticles (CuNPs) can be synthesized by green methods using plant extracts. These methods are more environmentally friendly and offer improved properties of the synthesized NPs in terms of biocompatibility and functional capabilities. Traditional medicine has a rich history of utilization of herbs for millennia, offering a viable alternative or complementary option to conventional pharmacological medications. Plants of traditional herbal use or those with medicinal properties are candidates to be used to obtain NPs due to their high and complex content of biocompounds with different redox capacities that provide a dynamic reaction environment for NP synthesis. Other synthesis conditions, such as salt precursor concentration, temperature, time synthesis, and pH, have a significant effect on the characteristics of the NPs. This paper will review the properties of some compounds from medicinal plants, plant extract obtention methods alternatives, characteristics of plant extracts, and how they relate to the NP synthesis process. Additionally, the document includes diverse applications associated with CuNPs, starting from antibacterial properties to potential applications in metabolic disease treatment, vegetable tissue culture, therapy, and cardioprotective effect, among others.

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Section: Relationship Of the Synthesis Process Variables And Cunp Pro...mentioning

confidence: 99%

Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications

Antonio-Pérez,

Durán-Armenta,

Pérez-Loredo

et al. 2023

Micromachines

View full text Add to dashboard Cite

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“…The extract of several plants parts such as leaves, roots, stem bark, flowers and seeds have been used in the fabrication of both metal NPs. For instance, Citrus limetta peels [ 8 ], aqueous extract of Cinnamon cassia [ 37 ], Allium sativum [ 38 ], Pelargonium sidoides [ 39 ], Leucosidea sericea (procyanidins) [ 40 , 41 ] have been used for the biological synthesis of both Au and Ag NPs. Additionally, the green synthesis entails the use of microorganisms such as bacteria, fungi, and viruses for producing metal NPs of immense biological functions.…”

Section: Synthesis and Characterization Of Metal Nanoparticlesmentioning

confidence: 99%

Recent advances on therapeutic potentials of gold and silver nanobiomaterials for human viral diseases

Ayipo

Bakare

Badeggi

et al. 2022

Current Research in Chemical Biology

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Viral diseases are prominent among the widely spread infections threatening human well-being. Real-life clinical successes of the few available therapeutics are challenged by pathogenic resistance and suboptimal delivery to target sites. Nanotechnology has aided the design of functionalised and non-functionalised Au and Ag nanobiomaterials through physical, chemical and biological (green synthesis) methods with improved antiviral efficacy and delivery. In this review, innovative designs, as well as interesting antiviral activities of the nanotechnology-inclined biomaterials of Au and Ag, reported in the last 5 years were critically overviewed against several viral diseases affecting man. These include influenza, respiratory syncytial, adenovirus, severe acute respiratory syndromes (SARS), rotavirus, norovirus, measles, chikungunya, HIV, herpes simplex virus, dengue, polio, enterovirus and rift valley fever virus. Notably identified among the nanotechnologically designed promising antiviral agents include AuNP-M2e peptide vaccine , AgNP of cinnamon bark extract and AgNP of oseltamivir for influenza, PVP coated AgNP for RSV, PVP-AgNPs for SARS-CoV-2, AuNRs of a peptide pregnancy-induce hypertension and AuNP nanocarriers of antigen for MERS-CoV and SARS-CoV respectively. Others are AgNPs of collagen and Bacillus subtilis for rotavirus, AgNPs labelled Ag30-SiO 2 for murine norovirus in water, AuNPs of Allium sativum and AgNPs of ribavirin for measles, AgNPs of Citrus limetta and Andrographis Paniculata for Chikungunya, AuNPs of efavirenz and stavudine , and AgNPs-curcumin for HIV, NPAuG3-S8 for HSV, AgNPs of Moringa oleifera and Bruguiera cylindrica for dengue while AgNPs of polyethyleneimine and siRNA analogues displayed potency against enterovirus. The highlighted candidates are recommended for further translational studies towards antiviral therapeutic designs.

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Physicochemical properties and in vitro stability studies of green synthesized gold nanoparticles using pelargonium sidoides

Cited by 2 publications

References 15 publications

Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications

Biosynthesis of Copper Nanoparticles with Medicinal Plants Extracts: From Extraction Methods to Applications

Recent advances on therapeutic potentials of gold and silver nanobiomaterials for human viral diseases

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