Physicochemical properties of deep eutectic solvents: A review

Omar, Karzan A.; Sadeghi, Rahmat

doi:10.1016/j.molliq.2022.119524

Cited by 230 publications

(102 citation statements)

References 136 publications

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“…According to the concept of green chemistry [ 43 , 44 ], in order to minimize the negative influence of the chemical industry on the environment, there is a need to reduce or even eliminate the usage of hazardous chemical substances including solvents, which should be replaced with environmentally friendly green solvents [ 45 , 46 ]. Apart from ionic liquids (IL) and supercritical fluids (SCF), the concept of green solvents also includes deep eutectic solvents (DES), which are mixtures of two or more individual components with a melting point of the mixture lower than the ones of its components [ 47 , 48 ]. While sharing many features with ionic liquids, DES are distinguishable from them mainly by the fact that they usually include non-ionic species as their constituents [ 49 ].…”

Section: Introductionmentioning

confidence: 99%

Quantification of Caffeine Interactions in Choline Chloride Natural Deep Eutectic Solvents: Solubility Measurements and COSMO-RS-DARE Interpretation

Jeliński¹,

Cysewski²

2022

IJMS

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Solubility of active pharmaceutical ingredients is an important aspect of drug processing and formulation. Although caffeine was a subject of many studies aiming to quantify saturated solutions, many applied solvents suffer from not being environmentally friendly. This work fills this gap by presenting the results of solubility measurements in choline chloride natural deep eutectic solvents, ccNADES, comprising one of seven of the following polyalcohols: glycerol, sorbitol, xylitol, glucose, sucrose, maltose and fructose. The ratio of ccNADES components was optimized for maximizing caffeine solubility at room temperature. Additionally, temperature dependent solubility was measured for the first four systems exhibiting the highest solubility potential, both in their neat forms and in mixtures with water. Results were used for intermolecular interactions assessments using the COSMO-RS-DARE approach, which led to a perfect match between experimental and computed solubility values. An important methodological discussion was provided for an appropriate definition of the systems. Surprising linear trends were observed between the values of fitting parameters and water-ccNADES composition. In addition, comments on selection of the values of the fusion thermodynamic parameters were provided, which led to the conclusion that COSMO-RS-DARE solubility computations can effectively compensate for the inaccuracies of these important physicochemical properties.

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Section: Introductionmentioning

confidence: 99%

Quantification of Caffeine Interactions in Choline Chloride Natural Deep Eutectic Solvents: Solubility Measurements and COSMO-RS-DARE Interpretation

Jeliński¹,

Cysewski²

2022

IJMS

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“…These solvents usually consist of two non-toxic components, one is the hydrogen bond acceptor (HBA) and the other is the hydrogen bond donor (HBD). Due to the formation of intramolecular hydrogen bonds, the melting point of the DES is lower than that of any of its components [26]. DES has good attributes including low toxicity, easy synthesis, non-flammability, and low vapor pressure [27].…”

Section: Introductionmentioning

confidence: 99%

Trace determination of triazine herbicides in fruit and vegetables using novel hydrophobic deep eutectic solvent‐based dispersive liquid‐liquid microextraction followed by high‐performance liquid chromatography‐ultraviolet

Jouybari

Shamsipur

et al. 2022

J of Separation Science

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“…The deep eutectic solvent (DES), as a new synthetic green solvent, has the advantages of low-cost effectiveness, non-volatility and good thermal stability [21][22][23]. However, some DES have the ability to inhibit bacteria, fungi and viruses due to the different composition of DES (hydrogen bond acceptor and hydrogen bond donor) and the chemical structure of the mixture [24]. NaOH as one of the most effective alkali [25,26], which is characterized by mild conditions, high lignin removal rate and high biogas yield, has been widely used in pretreatment process [27][28][29].…”

Section: Introductionmentioning

confidence: 99%

Determining Optimal Temperature Combination for Effective Pretreatment and Anaerobic Digestion of Corn Stalk

Li²,

Wachemo³

et al. 2022

IJERPH

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Temperature is one of the important factors affecting both chemical pretreatment and anaerobic digestion (AD) process of corn stalk (CS). In this work, the combined ways between pretreatment temperature (40 °C and 60 °C) and AD temperature (35 °C and 55 °C) were selected to investigate the AD performance for sodium hydroxide (NaOH) pretreated CS. Three organic loading rates (OLRs) of 1.6, 1.8 and 2.0 g·L−1·d−1 were studied within 255 days using continuously stirred tank reactors (CSTR). The results revealed that biogas yields of CS after pretreated were higher than that of untreated groups by 36.79–55.93% and 11.49–32.35%, respectively. When the temperature of NaOH pretreatment changed from 40 °C to 60 °C, there was no significant difference in enhancing the methane yields during the three OLRs. The mesophilic AD (MAD) of CS pretreated with 2% NaOH under 40 °C and 60 °C conditions produced 275 and 280 mL·gvs−1 methane yield at OLR of 1.6 g·L−1·d−1. However, as the OLR increased, the methane yield of CS under thermophilic AD (TAD) condition was further higher than under MAD condition. Furthermore, from the perspectives of energy balance and economic analysis, AD of 40 °C-treated CS recovered more energy and TAD is less expensive. Therefore, temperature of 40 °C was considered as an appropriate for pretreatment whether in mesophilic or thermophilic AD system. On the other hand, TAD was chosen as the optimal AD temperatures for higher OLRs.

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Physicochemical properties of deep eutectic solvents: A review

Cited by 230 publications

References 136 publications

Quantification of Caffeine Interactions in Choline Chloride Natural Deep Eutectic Solvents: Solubility Measurements and COSMO-RS-DARE Interpretation

Quantification of Caffeine Interactions in Choline Chloride Natural Deep Eutectic Solvents: Solubility Measurements and COSMO-RS-DARE Interpretation

Trace determination of triazine herbicides in fruit and vegetables using novel hydrophobic deep eutectic solvent‐based dispersive liquid‐liquid microextraction followed by high‐performance liquid chromatography‐ultraviolet

Determining Optimal Temperature Combination for Effective Pretreatment and Anaerobic Digestion of Corn Stalk

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