Phytochemical Analysis, Antibacterial Activity and Modulating Effect of Essential Oil from Syzygium cumini (L.) Skeels

Abstract

One of the main global problems that affect human health is the development of bacterial resistance to different drugs. As a result, the growing number of multidrug-resistant pathogens has contributed to an increase in resistant infections and represents a public health problem. The present work seeks to investigate the chemical composition and antibacterial activity of the essential oil of Syzygium cumini leaves. To identify its chemical composition, gas chromatography coupled to mass spectrometry was used. The antibacterial activity test was performed with the standard strains Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 25853 and Staphylococcus aureus ATCC 25923 and multidrug-resistant clinical isolates E. coli 06, P. aeruginosa 24 and S. aureus 10. The minimum inhibitory concentration (MIC) was determined by serial microdilution as well as the verification of the modulating effect of the antibiotic effect. In this test, the oil was used in a subinhibitory concentration. The test reading was performed after 24 h of incubation at 37 °C. The results show that the major chemical constituent is α-pinene (53.21%). The oil showed moderate activity against E. coli ATCC 25922, with the MIC of 512 µg/mL; there was no activity against the other strains. The oil potentiated the effect of antibiotics demonstrating possible synergism when associated with gentamicin, erythromycin and norfloxacin against E. coli 06 and S. aureus 10.

Chemical composition, antimicrobial and larvicidal activities of essential oils of two Syzygium species from Vietnam

“…Furthermore, both essential oils exhibited remarkable inhibitory activity against the yeast C. albicans. These results are consistent with data obtained for the antimicrobial activities of essential oils of some Syzygium plants (Shafi et al, 2002;Nadarajan and Pujari, 2014;Sarvesan et al, 2015;Siddique et al, 2015;Hamad et al, 2017;An et al, 2020;Fernandes et al, 2022).…”

“…Although the compositions of essential oils and biological activities of other Syzygium species are well-known (Kadir et al, 2022). Furthermore, several essential oils of Syzygium have been tried as mosquito larvicides as well as antimicrobials (Sarvesan et al, 2015;Siddique et al, 2015;Govindarajan and Benelli, 2016;Hamad et al, 2017;Benelli et al, 2018;Huong et al, 2022;Fernandes et al, 2022). However, to our best knowledge, there are no published reports on the chemical composition, antimicrobial and larvicidal activities of the essential oils of S. attopeuense and S. tonkinense.…”

EFECTO DE CAMPOS ELECTROMAGNÉTICOS PULSANTES DE 120 HERTZ Y CAMPOS MAGNÉTICOS ESTÁTICOS, SOBRE PARÁMETROS SANGUÍNEOS ENZIMÁTICOS DE RATAS (Rattus norvegicus) LÍNEA SPRAGUE DAWLEY

“…A resolução espontânea é rara, uma vez que em cerca de 70%-80% dos casos há evolução para a fase crônica, que é a forma mais grave. Com o passar do tempo e agravamento da situação, pode ocorrer o desenvolvimento de fibrose hepática, podendo evoluir para cirrose (cerca de 15 a 20%) e ainda carcinoma hepatocelular (CHC) MORGAN, 2006;MANNS et al, 2017;VALENTE;FERNANDES;TRINDADE, 2010; WORLD HEALTH ORGANIZATION, 2020) (Figura 1).…”

Chemical Composition, Antioxidant, Antibacterial, and Antibiofilm Activities of Backhousia citriodora Essential Oil

“…It belongs to a shrub of the Myrtaceae family. Numerous biological and pharmacological actions, such as antioxidant [ 29 ], antibacterial [ 30 ], and antifungal [ 31 ] actions, have been studied using EOs derived from several species of the Myrtaceae family. The fresh or dried leaves of BC have been widely used as ingredients in food flavorings, perfumes, and personal care products in Australia [ 32 ].…”