“…The values of the LogP coefficient (2.88) [ 12 ] and topological polar surface area (118 Å 2 ) [ 13 ] evidence the lipophilic nature of this compound, which largely determines its poor solubility in polar solvents. For this reason, UA is extracted from lichens using solvents such as acetone [ 5 , 10 , 14 , 15 , 16 , 17 , 18 , 19 , 20 ], dichloromethane [ 21 , 22 , 23 , 24 ], petroleum ether [ 3 , 4 , 25 ], n-hexane [ 26 ], and heptane [ 27 ]. Methanol and ethanol are also used as solvents, although much less frequently [ 4 , 28 , 29 ], as their extraction yields are lower than those of non-polar solvents.…”