Phytochemical Analysis, In Vitro Antioxidant, and Wound Healing Activities of Turbinaria ornata (Turner) J. Agardh from Gulf of Mannar, India

Abstract

Turbinaria ornata, tropical brown algae found in the South paci c and Indian Ocean ecosystems. In accordance with recent studies, Turbinaria ornata J. has potent anti-in ammatory effects. Therefore, this study is aimed to explore the biological activities of ethanolic extract of Turbinaria ornata J by analyzing the presence of phytochemical components, antioxidant property, antimicrobial activity and the wound healing activity. From the results, phytochemical analysis of ethanolic extract of T. ornata showed the presence of alkaloids, saponins, oils, total phenolic and total avanoid content were estimated to be 0.683 Abs and 0.433 Abs respectively. Anti-oxidant activity of the ethanolic extract of T. ornata extract showed remarkable DPPH radical scavenging activity of about 58.8% at 200μg/ml and total anti-oxidant activity of 0.257 absorbance at 100μg/ml concentration, as compared to that of their respective controls. The ethanolic extract of T. ornata exhibited the maximum zone of inhibition against the clinical pathogens like Pseudomonas aeuruginosa, Escherichia coli, Staphylococcus aureus, Candida albicans and Methicillin-resistant Staphylococcus aureus with their potent anti-microbial activity. Wound healing effects of the ethanolic extract of T. ornata was analysed by using Zebra sh model. The results showed the rapidand signi cant regeneration of the wounded caudal n on day 14. Therefore, the preliminary results of this study strongly supports the ethanolic extract of T. ornata may be effective in wound healing and regeneration of the wounded tissues. HighlightsAntioxidant and Antimicrobial activities ethanolic extract of T. ornata J. supports the in vitro biological properties.The ethanolic extract of T. ornata J. reveals the promising regenerative property in zebra sh model.T. ornata J. possess strong antioxidant, antimicrobial and regenerative properties.

Assessment of phytochemicals from marine algae Ulva fasciata and Dictyota dichotoma with antioxidant and antimicrobial potential

“…The presence of secondary metabolites is the basis for the development of biological activity [16] . For example, a study by Shaibi et al [17] on Turbinaria ornata listed the presence of alkaloids, saponins and fixed oils that exhibits various activities such as antioxidant and wound healing.…”

“…The obtained solvent extract was used to confirm secondary metabolites such as alkaloids, terpenoids, steroids, tannins, saponins, flavonoids, phenols, coumarins, quinines and glycosides via standard qualitative procedure [16,17] .…”

Antiviral activity of Turbinaria ornata against white spot syndrome virus in freshwater crab (Paratelphusa hydrodromous)

“…Fucoidans extracted from different seaweeds reported to inhibit the replication of several enveloped virus which includes HIV, HSV, and human cytomegalovirus (Thuy et al 2015) (Garrido et al 2017). Turbinaria ornata illustrated biological activity such as antibacterial, antioxidant antiin ammatory activity, and wound healing properties (Shaibi et al, 2021).…”

Structural characterization, antioxidant and anti-uropathogenic potential of biogenic silver nanoparticles using brown seaweed Turbinaria ornata

“…These bioactive compounds can reduce silver ions to silver and thus stabilize NPs ( Khan et al, 2022 ). According to published records, it has extensive biological properties such as anti-coagulant, antioxidant ( Arivuselvan et al, 2011 ; Alharbi et al, 2020 ), antitumor activity ( Remya et al, 2017 ), anti-inflammatory ( Ananthi et al, 2010 ; Subash et al, 2016 ), anti-cancer ( Bharath et al, 2021 ), antibacterial ( Ward and Deyab, 2016 ), anti-diabetic ( Unnikrishnan et al, 2014 ), and wound-healing ( Senthil and Annappan, 2013 ; Shaibi et al, 2022 ).…”