Phytochemical aspects and biological activities of essential oil of species of the family Canellaceae: A review

Abstract

Survey have proven the popular Canellaceae family use to treat various diseases such as: muscular pains, infections, stomatitis, anti-malaric, healing, among others. The main use of these species is in the extracts form and essential oils extracted from the leaves and stem. Highlighting the importance of this family on the pharmacological point of view and the fact that few studies in the literature have reported the characterization of the essential oils compounds and their respective biological activities. The objective of this study was to carry out a systematic review of previous studies on essential oils of the Canellaceae family species and their biological activities. The databases Scopus, Web of Science and PubMed were used for the search and a bibliographical manager was used. A total of 143 files were analyzed, of which 21 presented the phytochemical analysis and / or essential oils biological activities of these species. Few species have been studied so far, such as Canella winterana, Cinnamosma fragans, Cinnamosma madagascariensis, Cinnamodendron dinisii. It can be observed that the major constituents for these species essential oils were: 1,8-cineol, linalool, limonene, alpha and beta-pinene. And that the main proven activities were: antibiotic, antifungal, insecticide, larvicide, trypanocidal, cytotoxic, molluscicide, immunomodulatory, anti-inflammatory and anticonvulcionate. From this literature review, it was possible to identify species that have not yet started studies and possible activities of their essential oils, mainly due to the almost homogeneous presence of the major constituents, making possible new research as well as projects and programs.

Estimativa da área foliar de Cinnamodendron dinisii a partir das dimensões lineares

“…Cinnamodendron dinisii Schwanke (Sinônimo: Capsicodendron dinisii (Schwake, Occhioni) é uma espécie nativa do Brasil pertencente à família Canellaceae com folhas de formato elíptico, elíptico obovado-ovado a oblongo, subcoriáceas a coriáceas, com ápice agudo, obtuso a arredondado, base aguda, e pecíolo de 5 -10 mm de comprimento (GONZAGA; LÍRIO, 2020). Esta espécie merece uma atenção especial, por ser amplamente difundida em remanescentes de mata atlântica, tendo alto potencial medicinal devido as propriedades farmacológicas já comprovadas principalmente para os óleos essenciais extraídos das folhas tais como: antimicrobiana, antioxidante, citotóxica, leshimanicida e inseticida (ANDRADE et al, 2013;ANDRADE et al, 2015;VEDOVATTO et al, 2015;ANDRADE et al, 2016;LOURA et al, 2016;AMARAL et al, 2017;ANDRADE et al, 2018, OLIVEIRA et al, 2019. No entanto, apesar das atividades promissoras relatadas na literatura, esta espécie ainda carece de mais estudos quanto à parte fitoquímica e agronômicos para sua produção em larga escala das folhas para extração e obtenção dos princípios ativos.…”