Phytochemical Composition and Antibacterial Activity of Moroccan <i>Lavandula angustifolia</i> Mill.

Imane, Messaoudi Moussi; Filali, Houda; Amal, Ait Haj Said; Nayme, Kaotar; Timinouni, Mohammed; Rahmoune, Imane; Hakkou, F.

doi:10.1080/0972060x.2017.1363000

Cited by 30 publications

(14 citation statements)

References 26 publications

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“…1,8-Cineole is a terpene that is characterized as a main constituent of several aromatic plants' essential oil [24] is a major part of LAEO, which could be the suitable potential of LAEO as an enhancer in naproxen sodium gel. These results have been reported by other researchers previously [10,[25][26][27][28]. The formulations were prepared with Carbopol 934 as the gelling agent at the concentration of 1% Table 1.…”

Section: Discussionsupporting

confidence: 86%

Percutaneous Absorption Enhancer Properties of Lavandula Angustifolia Essential Oil on Percutaneous Absorption of Naproxen Sodium from Topical Gel

Iman

Rostamkalaei

Ataee

2021

Preprint

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The naproxen bioavailability via percutaneous route is low, and several technologies have been used to overcome the problem. Although the permeation enhancer properties of natural essential oils have been reported, there is no study to show the effectiveness of Lavandula angustifolia essential oil on the percutaneous absorption of naproxen sodium from a topical gel to overcome poor percutaneous absorption of naproxen. To this end, the naproxen topical gel was formulated using Carbopol 940 (as a gelling agent), and several vehicles. The results showed a greater level of penetration into (222.19 ± 24.87 vs. 107.65 ± 6.38 µg/cm 2 ) and across (22.07 ± 4.42 vs. 13.14 ± 2.87µg/cm 2 ) the skin layers for the formulation containing essential oil in comparison with the naproxen gel ( P < 0.05) . A significant antinociceptive property was observed in naproxen topical gel containing 0.5% essential oil in both the first and late phase of the formalin test. The effect was observed in the late phase of the tail-flick test too. In conclusion, the study demonstrated that Lavandula angustifolia essential oil significantly enhanced the percutaneous absorption of naproxen and the analgesic effects.

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Section: Discussionsupporting

confidence: 86%

Percutaneous Absorption Enhancer Properties of Lavandula Angustifolia Essential Oil on Percutaneous Absorption of Naproxen Sodium from Topical Gel

Iman

Rostamkalaei

Ataee

2021

Preprint

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“…The main compounds in lavender ( L. angustifolia ) are linalool (38.6%–76.9%), followed by lavandulol (4.1%–8.6%), coumarin (2.2%–21.8%), and terpinen-4-ol (0.3%–14.3%) [20] The lavender plays a sedative role similar to narcotic materials. There are several mechanisms of action for lavender to improve the sleep disorders, such as the acetylcholine secretion blocking and gamma-aminobutyric acid receptors interaction in the CNS [16].…”

Section: Discussionmentioning

confidence: 99%

Effect of Lavender on Sleep, Sexual Desire, Vasomotor, Psychological and Physical Symptom among Menopausal and Elderly Women: A Systematic Review

et al. 2019

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Objectives The present systematic review was conducted to compare the effect of lavender on the quality of sleep, sexual desire, and vasomotor, psychological and physical symptoms among menopausal and elderly women. Methods There were five electronic databases which selected to search respective articles which included were Scopus, PubMed, Web of Science, Google Scholar, and the Cochrane Library without any language restriction since the study inception to March 10, 2018. The quality of studies was assessed in accordance with a jaded scale. Results According to three trials, the lavender as utilized in a capsule form or aromatherapy could significantly improve the measured Pittsburgh Sleep Quality Index score ( P < 0.05) in the menopausal and elderly women. The aromatherapy with lavender improved sexual function ( P < 0.001), depression ( P < 0.001), anxiety ( P < 0.001), and physical ( P < 0.001) symptoms. Based on a trial, 66.7%, 70.0%, and 53.3% of subjects reported feelings of relaxation, happiness, and cleanness effects of having used lavender respectively. Conclusions The results suggested the effectiveness of the use of lavender either in capsule form or aromatherapy on the improved quality of sleep, depression, anxiety, sexual desire, and psychological and physical symptoms. These results, however, should be interpreted with caution considering the limitations of the study.

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“…Although the chemical compositions of lavender essential oil were studied by GC-MS in different literatures [4,5], there is no report on the separation and analysis of lavender essential oil by preparative gas chromatography (pGC), NMR and GC-MS equipped with three capillary columns of different polarities. This study could not only verify experimental results, but also the isolated monomer by pGC is of great help to the study of the activity of the single and composite component of lavender essential oil.…”

Section: Introductionmentioning

confidence: 99%

Study on Lavender Essential Oil Chemical Compositions by GC-MS and Improved pGC

Dong

Aimila

et al. 2020

Molecules

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Lavender essential oil from the aerial parts of Lavandula angustifolia Mill. was analyzed by GC-MS equipped with three capillary columns of different polarities, which were HP-1, HP-5 ms and HP-INNOWax. A total of 40 compounds were identified by GC-MS, accounting for 92.03% of the total essential oil compositions. Nineteen monomers were separated by column chromatography and improved preparative gas chromatography (pGC), six of which could not be retrieved from the NIST 14 (National Institute of Standards and Technology, USA; 14th edition) library database. Fifteen compounds were identified for the first time in lavender essential oil. The improved pGC not only doubled the efficiency but also greatly reduced the cost.

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Phytochemical Composition and Antibacterial Activity of Moroccan Lavandula angustifolia Mill.

Cited by 30 publications

References 26 publications

Percutaneous Absorption Enhancer Properties of Lavandula Angustifolia Essential Oil on Percutaneous Absorption of Naproxen Sodium from Topical Gel

Percutaneous Absorption Enhancer Properties of Lavandula Angustifolia Essential Oil on Percutaneous Absorption of Naproxen Sodium from Topical Gel

Effect of Lavender on Sleep, Sexual Desire, Vasomotor, Psychological and Physical Symptom among Menopausal and Elderly Women: A Systematic Review

Study on Lavender Essential Oil Chemical Compositions by GC-MS and Improved pGC

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