Phytochemical Composition and Bioactivity Assessment of Essential Oil of Cinnamomum bejolghota (Buch.-Ham.) Sweet from Xuan Son National Park, Vietnam

Abstract

Background and Objective: Cinnamomum bejolghota (Buch.-Ham.) Sweet, belonging to the Cinnamomum genus, was cited as a medicinal plant due to its essential oils. This study aimed to discover the chemical constituents and biological properties of the essential oil from the bark of C. bejolghota collected from Xuan Son National Park, Phu Tho Province, Vietnam. Materials and Methods: The bark essential oils of C. bejolghota were extracted by the hydrodistillation method and investigated by Gas Chromatography/Mass Spectrometry (GC/MS) and Gas Chromatography-Flame Ionization Detection (GC-FID). The antimicrobial feature of the essential oil was estimated using disc diffusion and microdilution broth assays. Results: The bark essential oils of C. bejolghota grown in Xuan Son National Park, Vietnam were obtained in yields of 1.1% (v/w, ±0.01). Major components of the essential oil were geraniol (26.2%), 1,8-cineole (24.73%), "-terpineol (9.30%) and terpinene-4-ol (3.90%). The bark essential oils of C. bejolghota displayed antimicrobial activity against the yeast S. cerevisiae and filamentous fungi F. oxysporum with minimum inhibitory concentrations of 500 ppm. Conclusion:The present study first represents phytochemical and bioactivity analysis of the essential oil of the C. bejolghota from Northern of Vietnam.