Phytochemical profile and biological activities of Bromelia antiacantha extracts

Abstract

Reports from popular medicine usually act as a basis for the development of new drugs from natural compounds with therapeutic actions for serious diseases and prevalence such as cancer. Bromelia antiacantha Bertol. is a species of the Bromeliaceae family, considered an unconventional food plant, found in the south and midwest regions of Brazil. Despite the high nutritional content and pharmacological potential of its fruits, few scientific studies report its biological actions. Thus, this study evaluates the phytochemical profile of aqueous and ethanol extracts obtained from B. antiacantha fruits, as well as their possible antioxidant, antitumor, and cytotoxic activities. The aqueous extract exhibited phenolic compounds and flavonoids, while ethanol extracts indicated the presence of flavonoids and coumarin in their composition, regardless of the region of collection. The ethanolic extract demonstrated a more promising antioxidant effect than the aqueous extract and also induced a significant inhibition in the viability of human cervical cancer cells of the SiHa strain. In addition, treatment with both extracts did not alter the viability of non-tumor cells of the immortalized human keratinocyte lineage (HaCaT). These results bring new data about extracts obtained from a native plant, edible and traditionally used in popular medicine, opening new perspectives for its possible therapeutic application.

Investigations on the chemical and bioactivity profile of Bromeliaceae Juss

“…The aqueous extract exhibited phenolic compounds and flavonoids, while the ethanolic extracts indicated the presence of flavonoids and coumarin in their composition, regardless of the collection region. The ethanolic extract demonstrated a more promising antioxidant effect than the aqueous extract and induced a significant inhibition in the viability of human cervical cancer cells of the SiHa strain (Rodrigues et al, 2021).…”

In vitro investigation on Pennisetum purpureum leaf extracts grown in Indonesia of phytochemical components, optical characteristics, and antioxidant-antibacterial activities

“…The widespread application of herbal remedies in the improvement of various ailments be attributed to their cultural acceptance, cost-effectiveness, perceived efficacy, and limited potential for adverse reactions (Sujarwo et al, 2015). Moreover, the consistent utilization of plant-based formulations can be linked to the existence of bioactive secondary compounds that exhibit significant biological properties (Twaij and Hasan, 2022;Rodrigues et al, 2024). Some noteworthy instances agents of pharmaceuticals found such as azithromycin, aspirin, amphotericin B, atropine, acyclovir, pilocarpine, curcumin, capsaicin, digitoxigenin, artemisinin, vinblastine, tubocurarine, and various others which extracted from plants and are commercially available for medical use (Gonfa et al, 2021;Mathur and Hoskins, 2017) that has emphasized the crucial role by medicinal plants (MPs) and the associated indigenous wisdom in providing essential pharmaceutically active ingredients for the management of various illnesses.…”

Ferruginoside D: A Novel Phenylethanoid from Verbascum leiocarpum

“…[1] Knowing the medicinal properties of the plants on earth is of great importance due to their contributions to human health and the economy of the countries. [2] Studies reporting the biological activities of the plant extracts serve as a reference for the discovery of plants with therapeutic potential for many diseases. [3] Türkiye is the host of many different kinds of plants because of having different geographical regions.…”

“…Natural products of herbal origin constitute a source of many bioactive substances used for therapeutic purposes [1] . Knowing the medicinal properties of the plants on earth is of great importance due to their contributions to human health and the economy of the countries [2] . Studies reporting the biological activities of the plant extracts serve as a reference for the discovery of plants with therapeutic potential for many diseases [3] .…”

“…Antioxidant activity results of isolated compounds(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15).…”