Phytochemical Screening and Antibacterial Activity of Senduduk Leaves (Melastoma malabathricum L.)

Abstract

Melastoma malabathricum L. leaves is a traditional plant native to tropical Asia, subtropical, and Pacific islands. This study aimed to investigate the antibacterial activity of senduduk leaves (Melastoma malabathricum L.) against bacteria Streptococcus pyogenes,and Klebsiella pneumonia. Method of extraction done by maceration using ethanol 70% to get the extract. The antibacterial activity of the extracts was determined by using Kirby-Bauer Disc Susceptibility Test and with a concentration of 25%, 50% and, 75%. The inhibition zone was recorded from senduduk leaves (Melastoma malabathricum L.) extract to indicate the highest antimicrobial activity from this plant. Based on the results of this study, the extract leaves can inhibit the growth of Streptococcus pyogenes in concentration 75% (21.8 mm) and Klebsiella pneumonia in concentration 75% (16 mm). The phytochemical analysis detected the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids. The findings may be helpful to future investigators in identifying alternative and new bioactive secondary metabolites like antibiotics to treat resistant human pathogens.

Diabetic Wound Healing and Antimicrobial Activities of Gels Melastoma malabathricum L. and Psidium guajava L. in Sprague Dawley Rats

“…Phytochemical Results. The bioactive components of the extract were flavonoids, tannins, steroid saponins, total phenol (6.08%, quercetin 0.31 mg, and antioxidant activity >31.25 ppm in a mixed section of Psidium guajava L. Melastoma malabathricum L. Additional research has shown alkaloids, flavonoids, saponins, tannins, terpenoids (20) , alkaloids, steroids, saponins, phenols, and tannins (21) . Melastoma candidum D. Don contains flavonoids, triterpenoids, steroids, saponins, tannins, and glycosides (26) .…”