Phytochemical screening and antibacterial activity of <i>Garcinia kola</i> seed extracts against pathogenic methicillin resistant <i>Staphylococcus aureus</i>

Abstract

The study was aimed to determine the phytochemical constituents and antibacterial activity of Garcinia kola seeds extracts against pathogenic Methicillin Resistant Staphylococcus aureus (MRSA). Total of 54 Staphylococcus aureus isolates from infected wound and urine were collec from Abubakar Imam Urology Center in Kano State, Nigeria over a period of seven month (December, 2016 to July, 2017), out of which 5 methicillin resistant isolates were found and tested against the extracts. Phytochemical screening of the seeds extract Alkaloid, Tannin, Saponin, and Cardiac glycoside, Flavonoid, Terpenoid, Phenols, Anthraquinone and Steroid. However, reducing sugar is absent. The antibacterial activity of the extracts against the isolates showed that ethanol e 15.25mm) when compared to aqueous extract (14.37mm). The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the extracts ranges from 12.5 100mg/ml of the extracts. Statistical analysis of the result showed that there is no significant different on the susceptibility of the organisms against the extracts. Findings from this work support the use of seed extracts from

Phytochemical Screening and Antibacterial Activities of Aframomum melegueta (K. Schum) Seed Extracts on Salmonella typhi and Klebsiella pneumoniae

“…The methanolic solvent gave better bactericidal effects (MBC) than the aqueous solvent. This observation was explained by Nas et al (2017), that organic solvents generally have better solubility than aqueous, hence higher concentration of bioactive constituents and better suppressive and lethal effects.…”