Phytochemical Screening and Antibacterial Activity of Citrus sinensis (L.) Osbeck [Orange] and Citrus aurantifolia (Cristm.) Swingle [Lime] Stem from Bacteria Associated with Dental Caries

Nata’ala, M. K.; Dalhat, Mahmood Hassan; Omoye, B. S.; Isah, A. A.; Kabiru, Sanusi Mohammed; Bashiru, I.; Umar, FA

doi:10.9734/jamb/2018/39134

Cited by 8 publications

(8 citation statements)

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“…B. pilosa is an upright herb from the family Asteraceae which grows in the tropics and temperate regions of West Africa. It originates from South America and is now distributed to all parts of the world [ 159 , 160 ]. In traditional medicine, the whole plant is used for the management of gastrointestinal disorders, ulcers, hypertension, bleeding and cardiovascular diseases.…”

Section: Resultsmentioning

confidence: 99%

A review on anti-peptic ulcer activities of medicinal plants used in the formulation of Enterica, Dyspepsia and NPK 500 capsules

Kumadoh

Archer

Yeboah

et al. 2021

Heliyon

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Peptic ulcer disease affects many people globally. With the increasing resistance to some orthodox antibiotics such as Clarithromycin and Metronidazole, it is important that new acceptable, safer and effective therapies are developed to manage this disease. Various herbal medicines have been used traditionally for the remedy of peptic ulcer disease (PUD), however scientific information with regards to their anti-peptic ulcer both in-vivo and invitro as well as clinical studies supporting their use is still inadequate. The Centre for Plant Medicine Research, (CPMR) Mampong-Akuapem, Ghana manufactures three herbal Products namely Enterica, Dyspepsia and NPK 500 capsules which are currently used for the remedy of PUD as a triple therapy at its out-patient clinic with promising effects. The aim of this review is to gather information from literature on the anti-ulcer properties, pharmacological, phytochemical constituents and related activities of herbal plants used at the CPMR for formulation of the triple herbal therapy. This review may, provide some scientific bases for the use of Enterica, Dyspepsia and NPK 500 capsules in the management of Peptic ulcer at the CPMR out-patient clinic. Methods: Organization for the review involved the on and/or offline search for information from available literature using electronic data and scientific research information resources such as PubMed, Science Direct and Google scholar. Results: In this review, fifteen ethno-medicinal plants used for the formulation of Enterica, Dyspepsia and NPK capsules have been discussed, presenting the description of the plants, composition and pharmacological activity. Interpretation: Tables with the summary of reviewed medicinal plants with their anti-ulcer models and inference on possible mechanisms of action were drawn up. The mechanism(s) of action of individual plants and products (Enterica, Dyspepsia and NPK 500 capsules) must be further investigated and established experimentally in-vitro in addition to in-vivo pharmacological and clinical activity studies to confirm their use in the remedy of PUD.

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Section: Resultsmentioning

confidence: 99%

A review on anti-peptic ulcer activities of medicinal plants used in the formulation of Enterica, Dyspepsia and NPK 500 capsules

Kumadoh

Archer

Yeboah

et al. 2021

Heliyon

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“…This antibacterial activity is beneficial for the treatment of dental caries [89]. In a similar study, the antibacterial effect of aqueous and alcoholic lime extracts on the main bacterial species causing caries was studied, noting that Citrus aurantifolia has antibacterial effects on C. pneumonia, S. aureus and P. mirabilis species [88]. These results are supported by similar studies [90] in which similar antibacterial effects of lime extract were observed, and, in addition, Pathan et al [91], demonstrated that C. aurantifolia has antimicrobial effects on E. coli species.…”

Section: Herbs As Therapeutic Agents In Dentistrymentioning

confidence: 99%

“…In terms of its use, lime has both beneficial medical and cosmetic effects. Regarding the chemical composition, it can be stated that Citrus aurantifolia is rich in carbohydrates, alkaloids, flavonoids, steroids, and anthraquinones [88]. In general medicine and dentistry, volatile lime oil is used.…”

Section: Herbs As Therapeutic Agents In Dentistrymentioning

confidence: 99%

Vegetal Compounds as Sources of Prophylactic and Therapeutic Agents in Dentistry

Milutinovici

Chioran

Buzatu

et al. 2021

Plants

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Dental pathology remains a global health problem affecting both children and adults. The most important dental diseases are dental caries and periodontal pathologies. The main cause of oral health problems is overpopulation with pathogenic bacteria and for this reason, conventional therapy can often be ineffective due to bacterial resistance or may have unpleasant side effects. For that reason, studies in the field have focused on finding new therapeutic alternatives. Special attention is paid to the plant kingdom, which offers a wide range of plants and active compounds in various pathologies. This review focused on the most used plants in the dental field, especially on active phytocompounds, both in terms of chemical structure and in terms of mechanism of action. It also approached the in vitro study of active compounds and the main types of cell lines used to elucidate the effect and mechanism of action. Thus, medicinal plants and their compounds represent a promising and interesting alternative to conventional therapy.

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“…The antifungal activity of the trona was carried out as described by Nata'ala et al [20]. A sample portion of 0.1 ml aliquot of each of the standardized fungal cell suspension was transferred onto the surface of the dried plate containing SDA.…”

Section: Test For Antifungal Activity Of the Tronamentioning

confidence: 99%

Potency of Trona on Fungi Associated with Tinea Capitis from Children in Usmanu Danfodiyo University Sokoto (UDUS)

Nata’ala

Mormoni

Isah

et al. 2018

SAJRM

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Aim: The potency of trona against fungi associated with dermatophytes isolated from children in Usmanu Danfodiyo University Sokoto (UDUS) local farming community was investigated. Place and Duration of Study: Department of Microbiology, Department of Pure and Applied Chemistry and Department of Pharmacognosy, Usmanu Danfodiyo University, Sokoto, Nigeria, between January 2017 and September 2017. Methodology: The samples were collected from errand children within UDUS, and the organisms were isolated and identified microscopically using standard methods. Elemental analysis of the two types of trona (red and white) was also determined using standard Analytical methods. The sensitivity test was carried out using agar well diffusion method. Results: In the two types of trona (red and white) Sodium was found to have the highest concentration of 9500 mg/kg and 8300 mg/kg, and the lowest was 0.15 and 0.10 mg/kg. Potassium was reported to have a concentration of 4400 mg/kg and 1800 mg/kg for the white and red trona respectively. Some of the organisms identified were Microsporum Canis, Trichophyton rubrum, Trichophyton mentagrophytes etc. Highest mean zone of inhibition of 20.7 and 23.3 mm was recorded for the red and white trona respectively. The least zone of inhibition recorded was 2.7 and 4.7 mm for the red and white trona respectively. Increased activity was recorded when the concentration of the trona was increased. Conclusion: The results revealed promising potentials of trona in the treatment of fungi associated with dermatophytoses. However, further studies should be done to determine the mechanism of action of trona on these organisms.

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Phytochemical Screening and Antibacterial Activity of Citrus sinensis (L.) Osbeck [Orange] and Citrus aurantifolia (Cristm.) Swingle [Lime] Stem from Bacteria Associated with Dental Caries

Cited by 8 publications

References 0 publications

A review on anti-peptic ulcer activities of medicinal plants used in the formulation of Enterica, Dyspepsia and NPK 500 capsules

A review on anti-peptic ulcer activities of medicinal plants used in the formulation of Enterica, Dyspepsia and NPK 500 capsules

Vegetal Compounds as Sources of Prophylactic and Therapeutic Agents in Dentistry

Potency of Trona on Fungi Associated with Tinea Capitis from Children in Usmanu Danfodiyo University Sokoto (UDUS)

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