Phytochemical screening and antimicrobial assessment of &lt;i&gt;Abutilon mauritianum, Bacopa monnifera and Datura stramonium&lt;/i&gt;

Banso, A; Adeyemo, S O

doi:10.4314/biokem.v18i1.56390

Cited by 83 publications

(78 citation statements)

References 9 publications

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“…Percentage yield of the extract = weight of extract (gm) / weight of Ocimum powder (gm) × 100 =13(gm) / 100(gm) × 100 = 13% (Banso and Adeyemo, 2006). This result is almost similar to the results of Tomar et al (2010) who found that the percentage recovery of ethanolic extract was 10.6% w/w from fine ocimum leaves powder which was extracted by using a soxhlet apparatus.…”

Section: Results and Discutions Extraction Of Ocimim Basilicummentioning

confidence: 99%

In vitro and in vivo Antibacterial Activity of Ethanolic Extract of Sweet Basil (Ocimum basilicum L.) Leaves against Escherichia coli in Experimentally Infected Rats

Ibrahim¹

2015

Adv. Anim. Vet. Sci.

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| The present study was carried out to investigate the antibacterial activity of ethanol extract of Ocimum basilicum against infectious diarrhea caused by E. coli. Two experiments were performed in this present study; the first one is in vitro antibacterial activity of Ocimum basilicum ethanolic extract. The second experiment included study in vivo antibacterial activity of the extract after inducing diarrhea with oral pathogenic E. coli in five rats groups (eight rats of each). The results of the in vitro antibacterial study showed that E. coli was more sensitive to ethanolic extract of O.B in comparison with Gentamicin and Amikacin and it was resistant to the metronidazole, but E. coli was more sensitive to Trimethoprim/Sulfamethoxazole. Two doses of O.B extract 100, 200 mg/kg. BW were used to treat this infection for fourteen days orally. The results of the in vivo study indicated that doses of 200 mg/kg BW O.B extract and 6.85 mg/kg. BW of Trimethoprim/Sulfamethoxazole were succeeded in returning the rectal E. coli count of infected rats to normal values before inducing infection in both kinds of therapy at the first week. Food intake, water intake and body weight significantly (P < 0.05) increased in comparison with others doses or groups. From the results obtained, it could be concluded that ethanolic extract of O.B leaves at dose 200 mg/kg. BW was more effective and safe in comparison with antibacterial agent and other O.B dose, this anti-diarrheal activity of O.B ethanolic extract may be due to its constituents of secondary metabolites that are responsible for the antibacterial activity with different mechanisms of action.

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Section: Results and Discutions Extraction Of Ocimim Basilicummentioning

confidence: 99%

In vitro and in vivo Antibacterial Activity of Ethanolic Extract of Sweet Basil (Ocimum basilicum L.) Leaves against Escherichia coli in Experimentally Infected Rats

Ibrahim¹

2015

Adv. Anim. Vet. Sci.

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“…Saponins are special classes of glycosides which have been reported to possess soapy properties and active microbial agents (Banso and Adeyemo 2006) Tannins have also been reported to prevent the development of microorganisms by precipitating microbial protein and making nutritional proteins unavailable to the (Sodipo et al, 1991). Alkaloids are poisonous but they have been proved to be useful in correcting renal disorders.…”

Section: Resultsmentioning

confidence: 99%

Nutritional values of flamboyant (Delonix regia) seeds obtained in Akure, Nigeria

Abulude¹,

Adejayan

2017

Preprint

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“…A few drops of 5% ferric chloride were then added. Black or blue-green coloration or precipitate was taken as positive result for the presence of tannins [10].…”

Section: Test For Tanninsmentioning

confidence: 99%

ANTIBACTERIA ACTIVITY OF PAPUAN ANT-NEST (MYRMECODIA PENDANSL.M. Perry) ETHANOL EXTRACT AGAINST SHIGELLA DYSENTERIAE

Kusuma¹,

Kusuma²,

Sulistiyaningsih³

2017

Asian J Pharm Clin Res

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Background: Shigella dysenteriae continues to be a major health problem in Indonesia, which usually leads to death, due to diarrhoea and dysentery, predominantly in children below the age of 5. Bacterial invasion of the colonic epithelium leads to severe inflammation together with bacterial dissemination generates abscesses and ulcerations. Myrmecodia pendans, also locally known by indigenous Papuans as ant-nest is native to Southeast Asia. This tropical plant has proven to be rich in bioactive constituents and highly valued as an alternative choice for cancer/tumor treatments and an efficacious herbal drug to prevent and cure diarrhea.Objective: This research aimed to determine antibacterial activity of Ant-nest extract against S. dysenteriae and to determine its minimum inhibitory concentration (MIC) -minimum bactericidal concentration (MBC) range of concentration.Methods: Ant-nest dried plant were obtained from Wamena, Papua. The extract was obtained by using maceration method with 70% ethanol as solvent. Antibacteria activity test were then performed by using perforated agar method with various extract concentration (10, 20, 40, and 60% (g/mL)). MIC-MBC concentration determinated by using microdilution method.Results: From 500.42 g dried plant we can obtain 77.47 g dry extract (15.48% rendement). Phytochemical screening result showed that the ethanol extracts of ant-nest contains metabolites such as alkaloids, flavonoids, tanins, saponins, and steroids/terpenoids. Largest inhibition zone was shown by 60% extract concentration with 1.74 ± 0.021 cm diameter. MIC -MBC concentrations lays in range of 14 -16 % (w/v). Conclusion:The results of the present investigation suggest that the extracts of the studied plants can be used as potential leads to discover new drugs to control some S. dysenteriae infections..

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Phytochemical screening and antimicrobial assessment of <i>Abutilon mauritianum, Bacopa monnifera and Datura stramonium</i>

Cited by 83 publications

References 9 publications

In vitro and in vivo Antibacterial Activity of Ethanolic Extract of Sweet Basil (Ocimum basilicum L.) Leaves against Escherichia coli in Experimentally Infected Rats

In vitro and in vivo Antibacterial Activity of Ethanolic Extract of Sweet Basil (Ocimum basilicum L.) Leaves against Escherichia coli in Experimentally Infected Rats

Nutritional values of flamboyant (Delonix regia) seeds obtained in Akure, Nigeria

ANTIBACTERIA ACTIVITY OF PAPUAN ANT-NEST (MYRMECODIA PENDANSL.M. Perry) ETHANOL EXTRACT AGAINST SHIGELLA DYSENTERIAE

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