Phytochemical Screening, GC-MS Analysis and Biological Activities of Extracts of Artemisia vulgaris Linn.

Chaudhary, Rashma; Maharjan, Binita; Bharati, Samjhana; Shrestha, Timila; Mishra, Pawan Kumar; Karanjit, Sangita; Bhattarai, Deval Prasad; Homagai, Puspa Lal; Shrestha, Ram Lal

doi:10.3126/arj.v2i01.40743

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…Presently, a substantial quantity of information on the phytochemical properties has been accumulated for the plant extracts, resulting from the application of chromatography in conjunction with mass spectrometry detection and various methods of ionization [ 68 , 69 , 70 ]. The same applies to extracts and essential oils of various species of Artemisia L. The details of their phytochemical composition, derived from both qualitative and quantitative studies and given in [ 71 , 72 , 73 , 74 , 75 ], demonstrate the extensive array of bioactive compounds found in Artemisia L.…”

Section: Resultsmentioning

confidence: 99%

Five Different Artemisia L. Species Ethanol Extracts’ Phytochemical Composition and Their Antimicrobial and Nematocide Activity

Nikitin,

Fitsev,

Egorova

et al. 2023

IJMS

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Among the plants that exhibit significant or established pharmacological activity, the genus Artemisia L. deserves special attention. This genus comprises over 500 species belonging to the largest Asteraceae family. Our study aimed at providing a comprehensive evaluation of the phytochemical composition of the ethanol extracts of five different Artemisia L. species (collected from the southwest of the Russian Federation) and their antimicrobial and nematocide activity as follows: A. annua cv. Novichok., A. dracunculus cv. Smaragd, A. santonica cv. Citral, A. abrotanum cv. Euxin, and A. scoparia cv. Tavrida. The study of the ethanol extracts of the five different Artemisia L. species using the methods of gas chromatography–mass spectrometry (GC–MS) and high-performance liquid chromatography–quadrupole time-of-flight mass spectrometry (HPLC–MS/MS) allowed establishing their phytochemical profile. The obtained data on the of five different Artemisia L. species ethanol extracts’ phytochemical composition were used to predict the antibacterial and antifungal activity against phytopathogenic microorganisms and nematocidal activity against the free-living soil nematode Caenorhabditis elegans. The major compounds found in the composition of the Artemisia L. ethanol extracts were monoterpenes, sesquiterpenes, flavonoids, flavonoid glycosides, coumarins, and phenolic acids. The antibacterial and antifungal activity of the extracts began to manifest at a concentration of 150 µg/mL. The A. dracunculus cv. Smaragd extract had a selective effect against Gram-positive R. iranicus and B. subtilis bacteria, whereas the A. scoparia cv. Tavrida extract had a selective effect against Gram-negative A. tumefaciens and X. arboricola bacteria and A. solani, R. solani and F. graminearum fungi. The A. annua cv. Novichok, A. dracunculus cv. Smaragd, and A. santonica cv. Citral extracts in the concentration range of 31.3–1000 µg/mL caused the death of nematodes. It was established that A. annua cv. Novichok affects the UNC-63 protein, the molecular target of which is the nicotine receptor of the N-subtype.

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Section: Resultsmentioning

confidence: 99%

Five Different Artemisia L. Species Ethanol Extracts’ Phytochemical Composition and Their Antimicrobial and Nematocide Activity

Nikitin,

Fitsev,

Egorova

et al. 2023

IJMS

View full text Add to dashboard Cite

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“…To determine the presence of major chemical constituents present in the plant extracts, phytochemical tests were carried out as per the standard protocols [18,19]. Briefly, the methods adopted for phytochemical tests are as follows.…”

Section: Phytochemical Testmentioning

confidence: 99%

Synthesis, characterization and antimicrobial study of silver nanoparticles using methanolic fraction of Artemisia vulgaris leaf

Parajuli,

Nepal,

Awasthi

et al. 2024

BIBECHANA

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Rational selection of active biomolecules in the synthesis of nanoparticles for reducing the precursor and functionalizing the nanoparticles (NPs) can offer remarkable comeback of biocompatibility and biological applicability. This work aimed at the synthesis of a cost-effective, ecofriendly, and a facile approach of silver nanoparticles (AgNPs) using methanolic leaf extract of Artemisia vulgaris. The phytochemical constituents present in the methanolic extract were characterized by qualitative chemical tests and spectroscopic measurements and employed for the reduction of silver nitrate into silver nanoparticles. Formation of AgNPs was monitored by UV-visible spectroscopic measurement. Fourier transform infrared (FTIR) spectroscopy reflected the presence of characteristic functional groups associated with the phytochemical constituents involved in the formation of nanoparticles. The crystalline phase and morphology of the NPs were assessed form X-ray diffraction (XRD) spectra and field emission scanning electron microscopy (FESEM), respectively. XRD pattern revealed the crystalline nature of nanoparticles with grain size of ∼ 28 nm based on the Debye Scherer formula. Study of antimicrobial activity of AgNPs against Gram-positive bacteria Bacillus subtili, Gram-negative bacteria Escherichia coli, and fungus Candida albicans exhibited good potential to control the bacterial and fungal growth.

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Biosynthesis of Essential Oils in Artemisia Species and Conservation through In Vitro Propagation

Verma¹,

Verma²

2023

Plants for Immunity and Conservation Strategies

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Phytochemical Screening, GC-MS Analysis and Biological Activities of Extracts of Artemisia vulgaris Linn.

Cited by 3 publications

References 17 publications

Five Different Artemisia L. Species Ethanol Extracts’ Phytochemical Composition and Their Antimicrobial and Nematocide Activity

Five Different Artemisia L. Species Ethanol Extracts’ Phytochemical Composition and Their Antimicrobial and Nematocide Activity

Synthesis, characterization and antimicrobial study of silver nanoparticles using methanolic fraction of Artemisia vulgaris leaf

Biosynthesis of Essential Oils in Artemisia Species and Conservation through In Vitro Propagation

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