Phytochemical screening, phenolic content and  antioxidant activity of Lavandula species extracts from Algeria

Haddouchi, Farah; Chaouche, Tarik Mohammed; Saker, Meriem; Ghellai, Imane; Boudjemai, Ouhiba

doi:10.26650/istanbuljpharm.2020.0051

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…This could be the case with plant extracts used traditionally for different purposes. For instance, LME contains different active compounds, including polyphenols, which can contribute to its beneficial effects, given the well-known antioxidant and anti-inflammatory properties ascribed to these compounds [ 20 ].…”

Section: Resultsmentioning

confidence: 99%

The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

et al. 2023

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Obesity is a worldwide public health problem whose prevalence rate has increased steadily over the last few years. Therefore, it is urgent to improve the management of obesity and its comorbidities, and plant-based treatments are receiving increasing attention worldwide. In this regard, the present study aimed to investigate a well-characterized extract of Lavandula multifida (LME) in an experimental model of obesity in mice and explore the underlying mechanisms. Interestingly, the daily administration of LME reduced weight gain as well as improved insulin sensitivity and glucose tolerance. Additionally, LME ameliorated the inflammatory state in both liver and adipose tissue by decreasing the expression of various proinflammatory mediators (Il-6, Tnf-α, Il-1β, Jnk-1, Pparα, Pparγ, and Ampk) and prevented increased gut permeability by regulating the expression of mucins (Muc-1, Muc-2, and Muc-3) and proteins implicated in epithelial barrier integrity maintenance (Ocln, Tjp1, and Tff-3). In addition, LME showed the ability to reduce oxidative stress by inhibiting nitrite production on macrophages and lipid peroxidation. These results suggest that LME may represent a promising complementary approach for the management of obesity and its comorbidities.

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Section: Resultsmentioning

confidence: 99%

The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

et al. 2023

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Traditional use of polar extracts from lavender flowers – systematic review of literature data

Dolzhko,

Melnyk,

Kruk

et al. 2024

Prosp. Pharm. Sc.

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Lavender is one of the most popular herbal medicines used to treat mild mood disorders like anxiety and depression. The most cultivated species is Lavandula officinalis, which has a diverse traditional use. This plant is valued for antibacterial, antifungal, hypolipidemic, antioxidant, neuroprotective, anti-aging, diuretic, sedative, hypnotic, anxiolytic and antidepressant properties. However, most often it is used as a water extract for treatment of mild mood disorders (restlessness, insomnia) as additional therapy. Most of the studies were dedicated to the volatile compounds contained in lavender flowers, but few of them were focused on water extract, which contains fewer essential oils, but more polar natural products (polyphenols and other non-volatile compounds). This medicinal plant species is rich in phytochemicals belonging to different chemical groups, including phenolic acids, phenolic aldehydes and flavonoids. Pharmacotherapy of mild mood disorders with infusion of lavender can improve quality of life, so that’s why it needs to be investigated more.

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Phytochemical screening, phenolic content and antioxidant activity of Lavandula species extracts from Algeria

Cited by 2 publications

References 5 publications

The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice

Traditional use of polar extracts from lavender flowers – systematic review of literature data

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