Phytochemicals as Antibacterial Agents: Current Status and Future Perspective

Nag, Swagata; Singh, Nutan; Kumaria, Suman

doi:10.1007/978-981-19-1854-4_2

Cited by 3 publications

(2 citation statements)

References 118 publications

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“…In the last few years, encapsulated EOs have gained popularity in wound treatment [183]. [161,192,196,[202][203][204] Carvacrol Disintegrates the cell membrane; changes fatty acid composition.…”

Section: Essential Oilsmentioning

confidence: 99%

An Overview of Biofilm-Associated Infections and the Role of Phytochemicals and Nanomaterials in Their Control and Prevention

Damyanova,

Dimitrova,

Borisova

et al. 2024

Pharmaceutics

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Biofilm formation is considered one of the primary virulence mechanisms in Gram-positive and Gram-negative pathogenic species, particularly those responsible for chronic infections and promoting bacterial survival within the host. In recent years, there has been a growing interest in discovering new compounds capable of inhibiting biofilm formation. This is considered a promising antivirulence strategy that could potentially overcome antibiotic resistance issues. Effective antibiofilm agents should possess distinctive properties. They should be structurally unique, enable easy entry into cells, influence quorum sensing signaling, and synergize with other antibacterial agents. Many of these properties are found in both natural systems that are isolated from plants and in synthetic systems like nanoparticles and nanocomposites. In this review, we discuss the clinical nature of biofilm-associated infections and some of the mechanisms associated with their antibiotic tolerance. We focus on the advantages and efficacy of various natural and synthetic compounds as a new therapeutic approach to control bacterial biofilms and address multidrug resistance in bacteria.

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Section: Essential Oilsmentioning

confidence: 99%

An Overview of Biofilm-Associated Infections and the Role of Phytochemicals and Nanomaterials in Their Control and Prevention

Damyanova,

Dimitrova,

Borisova

et al. 2024

Pharmaceutics

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“…Their anti-carcinogenic effects are attributed to interfering with the carcinogen’s interaction with cellular DNA, changing intracellular signalling pathways as a result of preventing the progression of an initiated cell through pre-neoplastic changes into a malignant cell, hindering angiogenesis, causing cell cycle arrest, and inducing apoptosis [ 175 , 176 , 177 ]. It is thought that the apoptosis induced by chemoprevention medicines may not only limit the carcinogenesis induced by carcinogens, but also suppress the growth of tumour and improve the cytotoxic effects of antitumour drugs on tumour, which plays a key role in the antitumour therapies [ 178 ].…”

Section: Anticancer Potentialmentioning

confidence: 99%

An Update on the Therapeutic Anticancer Potential of Ocimum sanctum L.: “Elixir of Life”

et al. 2023

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In most cases, cancer develops due to abnormal cell growth and subsequent tumour formation. Due to significant constraints with current treatments, natural compounds are being explored as potential alternatives. There are now around 30 natural compounds under clinical trials for the treatment of cancer. Tulsi, or Holy Basil, of the genus Ocimum, is one of the most widely available and cost-effective medicinal plants. In India, the tulsi plant has deep religious and medicinal significance. Tulsi essential oil contains a valuable source of bioactive compounds, such as camphor, eucalyptol, eugenol, alpha-bisabolene, beta-bisabolene, and beta-caryophyllene. These compounds are proposed to be responsible for the antimicrobial properties of the leaf extracts. The anticancer effects of tulsi (Ocimum sanctum L.) have earned it the title of “queen of herbs” and “Elixir of Life” in Ayurvedic treatment. Tulsi leaves, which have high concentrations of eugenol, have been shown to have anticancer properties. In a various cancers, eugenol exerts its antitumour effects through a number of different mechanisms. In light of this, the current review focuses on the anticancer benefits of tulsi and its primary phytoconstituent, eugenol, as apotential therapeutic agent against a wide range of cancer types. In recent years, tulsi has gained popularity due to its anticancer properties. In ongoing clinical trials, a number of tulsi plant compounds are being evaluated for their potential anticancer effects. This article discusses anticancer, chemopreventive, and antioxidant effects of tulsi.

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Molecular responses to clove and oregano essential oils are associated with reduced inflammation and improved gut barrier function in broiler chickens

Park,

Nam,

Ravichandran

et al. 2025

Poultry Science

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Phytochemicals as Antibacterial Agents: Current Status and Future Perspective

Cited by 3 publications

References 118 publications

An Overview of Biofilm-Associated Infections and the Role of Phytochemicals and Nanomaterials in Their Control and Prevention

An Overview of Biofilm-Associated Infections and the Role of Phytochemicals and Nanomaterials in Their Control and Prevention

An Update on the Therapeutic Anticancer Potential of Ocimum sanctum L.: “Elixir of Life”

Molecular responses to clove and oregano essential oils are associated with reduced inflammation and improved gut barrier function in broiler chickens

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