Phytochemicals-based targeting RdRp and main protease of SARS-CoV-2 using docking and steered molecular dynamic simulation: A promising therapeutic approach for Tackling COVID-19

Attitude of parents toward vaccination against COVID-19 for own children in Jordan: A cross-sectional study

“…Similarly, the EU approved Moderna mRNA for administration to older children 12 and up in July 2021. All these approvals were based on positive short-term trial results [ 6 , 7 ]. Vaccine against COVID-19 recommendations vary by country, especially when it comes to children.…”

Repurposing FDA-approved drugs cetilistat, abiraterone, diiodohydroxyquinoline, bexarotene, and remdesivir as potential inhibitors against RNA dependent RNA polymerase of SARS-CoV-2: A comparative in silico perspective

“…During simulation, the protein's structural alterations and insights from RMSD analysis support the protein's stability and equilibrium. The higher stability of the protein-ligand complex is indicated by the lower RMSD value of the protein backbone [ 55 ]. Fig.…”

3D printed human organoids: High throughput system for drug screening and testing in current COVID‐19 pandemic

“…As they are genetically unique to each patient, tissue organoid has provided alternative ways of preclinical drug testing and are now being used for the development of “personalized medicine” for several diseases. Organoids have been effectively generated and their application has been demonstrated in various fields, including drug screening, disease modeling, tissue transplant, pathogenesis, and regenerative medicine (Ashok et al, 2020; Parihar, Ferdous Sonia, et al, 2022; Parihar, Puranik, et al, 2022; Parihar, Sonia, et al, 2022; Parihar, Zafar, et al, 2022). In vitro models are more reproducible, permitting a larger sample size to be evaluated on multiple models in a smaller duration of time.…”