Phytochemistry and Antioxidant Activity of Soursop (Annona Muricata) Leaves

Abstract

Objective: Soursop (Annona muricata) is a tropical plant which has been utilized as a folk medicine to treat many diseases including cancer, inflammation and parasitic infection. In this study, we investigated its phytochemistry properties and antioxidant activity against free radicals.
 Methods: Annona muricata leaves were extracted in three different solvents: ethanol, ethyl acetate and n-hexane. Afterwards, a phytochemistry test and the thin layer chromatography (TLC) method were used to evaluate bioactive compounds contained in the three different extracts. Antioxidant activity from the semi-polar (ethyl acetate) and polar (ethanol) solvents were evaluated by the DPPH (1,1-diphenyl-2-picrylhydrazyl) method, and the antioxidant activity is expressed by IC50 value. The results were compared to ascorbic acid as a positive control.
 Results: The phytochemistry test showed that the extracts were positive for flavonoids, steroids, alkaloids, glycosides and tannins. Moreover, TLC analysis revealed that there were three chemical compounds contained in the extracts. The results from the DPPH method were that ethanolic extract was shown to have the most potent antioxidant activity with an IC50 value of 35.51 ppm.
 Conclusion: The ethanolic extract of Annona muricata could be developed as the next promising natural antioxidant source.

Phytochemical Study and Antioxidant Activity of Annona muricata (Annonaceae) and Corchorus olitorius (Tiliaceae) Two Medicinal Plants from the Ivorian Pharmacopoeia Used in the Treatment of Diabetes

“…In addition, the presence of alkaloids in leaves, seeds, roots and stem bark has been reported by Zine et al, (2018). However, our results differ from those of some authors such as Qorina et al, (2019) who demonstrated the presence of alkaloids and gall tannins from the extract of Annona muricata leaves using other solvents (ethanol, methanol, n-hexane and ethyl acetate). In addition, the presence of alkaloids is also noted in the methanolic extract of the leaves of Corchorus olitorius (Sadat et al, 2017).…”

The Influence of Catharanthus Roseus (L.) G. Don. Ethanol Extract in Clove Oil Nanoemulsion: Physical Characterization, Antioxidant and Antibacterial Activities

“…The result was then compared with ascorbic acid as the positive control. The IC50 value was used as an indicator for antioxidant activity based on previous study [31,32].…”

Kajian Pengaruh Penyeduhan terhadap Kadar Total Fenol Teh Herbal Biji Ketumbar dan Daun Sirsak

“…Hal ini juga sesuai dengan pernyataan Hasan et al, (2020); Jannah et al, (2017); Olugbuyiro. et al, (2014); Qorina et al, (2019) bahwa ekstrak daun sirsak mengandung alkaloid, tanin, saponin, flavonoid dan fenolik. Penelitian Hasmila et al, (2019); Purnamasari et al, (2020); Usunobun et al, (2014) menunjukkan ekstrak etanol daun sirsak mengandung alkaloid, saponin, flavonoid, tanin dan fenolik.…”