Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a

Gomes, Roosevelt Albuquerque; Teles, Yanna Carolina Ferreira; Pereira, Fillipe de Oliveira; Rodrigues, Luís Alberto de Sousa; Lima, Edeltrudes de Oliveira; Agra, Maria de Fátima; Souza, María de Fátima Vanderlei de

doi:10.1590/s1984-82502015000400012

Cited by 14 publications

(8 citation statements)

References 24 publications

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“…Pheophytin a ( 3 ), 13 2 -hydroxy-(13 2 - S )-pheophytin a ( 4a ), 13 2 -hydroxy-(13 2 - R )-pheophytin a ( 4b ), Pheophytin b ( 5 ), green solids, were identified by 1D and 2D NMR and comparison with the literature [ 12 , 13 , 14 ].…”

Section: Resultsmentioning

confidence: 99%

New Sulphated Flavonoids and Larvicidal Activity of Helicteres velutina K. Schum (Sterculiaceae)

et al. 2018

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Helicteres velutina K. Schum (Sterculiaceae), commonly known in Brazil as ‘pitó’, is traditionally used by indigenous peoples as insecticides and repellents. The present work reports on the the phytoconstituents from aerial parts of H. velutina and evaluation of the larvicidal potential of its extract. The compounds were isolated using chromatographic techniques and identified by NMR, IR and LC-HRMS. This study led to the isolation of a fatty acid, one aliphatic alcohol, four chlorophyll derivatives, one steroid, triterpenes, a lignan, and flavonoids, highlighting the new compounds in the literature, 5,4′-di-hydroxy-7-methoxy-8-O-sulphate flavone (mariahine) (15a) and 5,3′-di-hydroxy-7,4′-dimethoxy-8-O-sulphate flavone (condadine) (15b). The work presented here contributes to the chemotaxonomic knowledge of the Sterculiaceae family by describing the occurrence of sulphated flavonoids in this family for the first time. The crude ethanolic extract of H. velutina featured robust larvicidal activity against Aedes aegypti larvae, showing that the extract can be useful as a domestic larvicide, just as indicated by traditional use, to combat A. aegypti, a vector insect of severe viral diseases, such as dengue and Zika.

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Section: Resultsmentioning

confidence: 99%

New Sulphated Flavonoids and Larvicidal Activity of Helicteres velutina K. Schum (Sterculiaceae)

et al. 2018

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“…Also, pheophytin a, a chlorophyll derivative of Malvaceae, exhibited strong antimicrobial effects against both Gram‐positive and ‐negative bacteria, as well as Candida spp. (Gomes et al, ). Another compound, malvone A extracted from M. sylvestris stems, appears to be the most active ingredient and responsible for the antimicrobial potential of this plant (Veshkorova et al, ).…”

Section: Pharmacological Properties Of Malva Plantsmentioning

confidence: 99%

“…Also, pheophytin a, a chlorophyll derivative of Malvaceae, exhibited strong antimicrobial effects against both Gram-positive and -negative bacteria, as well as Candida spp. (Gomes et al, 2015).…”

Section: Antimicrobial Activities Of Malva Plantsmentioning

confidence: 99%

Malva species: Insights on its chemical composition towards pharmacological applications

Sharifi‐Rad

Melgar‐Lalanne

Hernández-Álvarez

et al. 2019

Phytotherapy Research

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Malvaceae family is typical from the Mediterranean region, contains 240 genera and more than 4,200 species. They are most commonly used as ornamental plants, although they can also be conceived as a food resource and remedy for various diseases, such as digestive, respiratory, genitourinary, throat infections, and skeletal and skin disorders, as also injuries where they are profoundly applied for skin care and as antiseptic and demulcent. They also possess diuretic, lenitive, spasmolytic, and laxative effects, besides to be used as antidiarrheal. Thus, the present review provides in‐depth data on Malva spp. potential applications and phytochemical composition for food and pharmaceutical industries. Habitat and cultivation conditions and the clinical reports related to its biological effects are also emphasized. Malva spp. possess a wide variety of chemical constituents (such as polysaccharides, coumarins, flavonoids, polyphenols, vitamins, terpenes, and tannins) found in different plant organs, especially in leaves and flowers, connected to their biological activity. In general, Malva spp. have rather moderate antimicrobial activity, high antiinflammatory and wound healing activities, strong antioxidant activity, and anticancer properties. Results from in vitro and in vivo experiments encourage more in‐depth studies, namely clinical trials, towards to improve knowledge on the use of Malva spp. for the treatment of various health conditions in humans.

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“…Previously, pheophytin a has been reported to possess antimicrobial activity against Candida albicans (ATCC 90028) and C. albicans (ATCC 76615) [12] as well as antioxidant activity [13]. Amyrin (α) has been reported to exhibit antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, C. albicans, Staphylococcus aureus and Trichophyton mentagrophytes [14].…”

Section: Resultsmentioning

confidence: 99%

Phaeophytin and Triterpenoids from Brachystelma togoense Schltr, a Nigerian Medicinal Herb

Ekalu

Ayo

Habila

et al. 2019

AJOCS

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The medicinal herb Brachystelma togoense schtlr (Apocynaceae) is used traditionally for treatment of ailments. The secondary metabolites, phaeophytin a, α-amyrin and lupeol were isolated from the CH2Cl2 and MeOH extracts of Brachystelma togoense. The structures were elucidated using 1H, 13C and 2D NMR. These phytochemicals have previously being reported to have various biological activities such as anti-inflammatory, anti-fungal and anti-cancer. The presence of phaeophytin a, α-amyrin and lupeol in Brachystelma togoense justified the use of the plant for medicinal purpose in Nigeria.

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Phytoconstituents from Sidastrum micranthum (A. St.-Hil.) Fryxell (Malvaceae) and antimicrobial activity of pheophytin a

Cited by 14 publications

References 24 publications

New Sulphated Flavonoids and Larvicidal Activity of Helicteres velutina K. Schum (Sterculiaceae)

New Sulphated Flavonoids and Larvicidal Activity of Helicteres velutina K. Schum (Sterculiaceae)

Malva species: Insights on its chemical composition towards pharmacological applications

Phaeophytin and Triterpenoids from Brachystelma togoense Schltr, a Nigerian Medicinal Herb

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