Pikuroside:  A Novel Iridoid from <i>Picrorhiza</i> <i>kurroa</i>

Jia, Qi; Hong, Mei-Feng; Minter, David E.

doi:10.1021/np980493+

Cited by 64 publications

(28 citation statements)

References 14 publications

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“…54, No. 8 ϭ1.0 Hz) between H-9 (d 2.59) and H-10b (d 4.00), as observed in the case of pikuroside (7), 2) indicating that H-7 could be in b position. The acetal linkage between C-3 and C-10 was confirmed by HMBC correlations (Fig.…”

Section: Iridoids From Neopicrorhiza Scrophulariiflora and Their Hepamentioning

confidence: 59%

Iridoids from Neopicrorhiza scrophulariiflora and Their Hepatoprotective Activities in Vitro

Wang

Xiong

et al. 2006

Chem. Pharm. Bull.

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Section: Iridoids From Neopicrorhiza Scrophulariiflora and Their Hepamentioning

confidence: 59%

Iridoids from Neopicrorhiza scrophulariiflora and Their Hepatoprotective Activities in Vitro

Wang

Xiong

et al. 2006

Chem. Pharm. Bull.

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“…About 500 μl of 1 M NaOH and 275 μl of distilled H 2 O were added to the mixture, mixed well and the intensity of pink color was measured at 510 nm. The level of total flavonoid concentration was calculated using quercetin (QU) as a standard ( Jia et al, 1999). The results were expressed as mg of quercetin equivalents per g of dry extract.…”

Section: Determination Of Total Flavonoid Contentsmentioning

confidence: 99%

Comparison of Antioxidant and Antimicrobial Properties for Ginkgo biloba and Rosemary (Rosmarinus officinalis L.) from Egypt

El-Beltagi

Badawi

2013

Not Bot Hort Agrobot Cluj

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The widespread use of medicinal plants for health purposes has increased dramatically due to their great importance to the public health. In this study levels of phenolic, flavonoid contents of Ginkgo biloba and Rosmarinus officinalis from Egypt were determined. HPLC was used to identify and quantify the phenolic compounds in selected plants. The plant extracts were evaluated for their antioxidant activities using various antioxidant methodologies, (i) scavenging of free radicals using 2, 2-diphenyl-1-picrylhydrazyl, (ii) metal ion chelating capacity, and (iii) scavenging of superoxide anion radical. The antimicrobial activity of both plant's extracts were evaluated against a panel of microorganisms by using agar disc diffusion method. The total phenolic content (75.30 and 98.31 mg/g dry weight in G. biloba and R. officinalis, respectively) was significantly (p<0.05) different. Among the identified phenolic compounds, quercetin, kaempferol and caffeic acid were the predominant phenolic compounds in Ginkgo biloba, whereas carnosic acid, rosmarinic acid, narinigen and hispidulin were the predominant phenolic compound in Rosmarinus officinalis leaves. The antioxidant activity increased with the concentration increase. The R. officinalis was more active than G. biloba extract against Gram-negative bacteria. This study reveals that the consumption of these plants would exert several beneficial effects by virtue of their antioxidant and antimicrobial activities.

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“…About 500 ml of 1M NaOH and 275 ml of distilled H2O were added to the mixture, mixed well and the intensity of color was measured at 510 nm. The content of total flavonoid concentration was calculated using quercetin (QU) as a standard (Jia et al, 1999). The results were expressed as mg of quercetin equivalents per gram of grape seed dry matter (mg QU/g DW).…”

Section: Determination Of Total Flavonoids Contentsmentioning

confidence: 99%

Synergistic Antioxidant Scavenging Activities of Grape Seed and Green Tea Extracts against Oxidative Stress

El-Beltagi

El-Desouky

Yousef

2016

Not Bot Horti Agrobo

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Grape seed and green tea extracts are reported to produce antioxidant scavenging activities against free radical toxicity. This study aimed to investigate the hypothesis that a specific combination of these extracts presents a synergistic antioxidant scavenging activities. The extracts of grape seed, green tea and their mixtures were characterized by phytochemical studies and tested for phenolics and flavonoids. In vitro antioxidant activity for individual extract and its mixtures was determined by DPPH, hydroxyl and superoxide free radical scavenging methods. The amount of total phenolics varied among the different extracts and ranged from 43.74 to 67.68 mg of gallic acid equivalents (GAE) / g dry weight, whereas total flavonoids content ranged from 4.25 to 11.66 mg of quercetin equivalents (QU) /g dry weight. The present results suggest that both extracts reported a highly contents of total phenolic and flavonoids compounds, also the mixtures of these extracts can synergistically enhance antioxidant activity. Antioxidant potential from mixture 2 (grape seed extract 200 mg: green tea extract 100 mg) was comparable to that of standard. HPLC results showed that the most abundant components in the mixture 2 extract were epigallocatechingallate while the lowest was the procyanidine.

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Pikuroside: A Novel Iridoid from Picrorhiza kurroa

Cited by 64 publications

References 14 publications

Iridoids from Neopicrorhiza scrophulariiflora and Their Hepatoprotective Activities in Vitro

Iridoids from Neopicrorhiza scrophulariiflora and Their Hepatoprotective Activities in Vitro

Comparison of Antioxidant and Antimicrobial Properties for Ginkgo biloba and Rosemary (Rosmarinus officinalis L.) from Egypt

Synergistic Antioxidant Scavenging Activities of Grape Seed and Green Tea Extracts against Oxidative Stress

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