Pineal Cyst without Hydrocephalus: Clinical Presentation and Postoperative Clinical Course After Infratentorial Supracerebellar Resection

Damaty, Ahmed El; Fleck, Steffen; Matthes, Marc; Baldauf, Jörg; Schroeder, Henry W. S.

doi:10.1016/j.wneu.2019.05.200

Cited by 20 publications

(25 citation statements)

References 34 publications

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“…Individual participant data was collected to organize the study characteristics table. Original languages of publications included Czech, German, and Japanese for one article each, Spanish in two publications, and English for the remainder [14,15,[20][21][22][23].…”

Section: Bibliography Detailsmentioning

confidence: 99%

“…PCs in the general population are mostly considered normal anatomical variations and the Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00381-020-04792-3) contains supplementary material, which is available to authorized users. parameters to define pathological PCs in need of treatment are currently unestablished [10][11][12][13][14][15][16][17][18][19][20][21].…”

Section: Introductionmentioning

confidence: 99%

“…As such, surgically treated pediatric PCs may represent a different and unique entity in clinical practice, which has not previously been properly investigated. Only a few large series on surgically treated PCs have been published in recent years [10][11][12][13][14][15][16][17][18][19][20][21][22], and no clinical study on surgically treated PCs in pediatric patients has been reported thus far. In 2013, a review on surgically treated PCs in children was performed.…”

Section: Introductionmentioning

confidence: 99%

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Systematic review of pineal cysts surgery in pediatric patients

et al. 2020

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Introduction We present a consecutive case series and a systematic review of surgically treated pediatric PCs. We hypothesized that the symptomatic PC is a progressive disease with hydrocephalus at its last stage. We also propose that PC microsurgery is associated with better postoperative outcomes compared to other treatments. Methods The systematic review was conducted in PubMed and Scopus. No clinical study on pediatric PC patients was available. We performed a comprehensive evaluation of the available individual patient data of 43 (22 case reports and 21 observational series) articles. Results The review included 109 patients (72% females). Ten-year-old or younger patients harbored smaller PC sizes compared to older patients (p < 0.01). The pediatric PCs operated on appeared to represent a progressive disease, which started with unspecific symptoms with a mean cyst diameter of 14.5 mm, and progressed to visual impairment with a mean cyst diameter of 17.8 mm, and hydrocephalus with a mean cyst diameter of 23.5 mm in the final stages of disease (p < 0.001). Additionally, 96% of patients saw an improvement in their symptoms or became asymptomatic after surgery. PC microsurgery linked with superior gross total resection compared to endoscopic and stereotactic procedures (p < 0.001). Conclusions Surgically treated pediatric PCs appear to behave as a progressive disease, which starts with cyst diameters of approximately 15 mm and develops with acute or progressive hydrocephalus at the final stage. PC microneurosurgery appears to be associated with a more complete surgical resection compared to other procedures.

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Section: Bibliography Detailsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Systematic review of pineal cysts surgery in pediatric patients

et al. 2020

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“…All pediatric and adult patients obtained a CCOS over 11, which represents a good/optimal result after microneurosurgery. [8,16] As observed in the immediate mRS, the resolution of the symptoms was obtained soon after the surgical resection. is could explain the relatively short clinical follow-up in some patients.…”

Section: Postoperative Outcomementioning

confidence: 67%

“…e CCOS was introduced by Majovsky et al for the evaluation of PC surgery. [8,16] e CCOS evaluates the clinical outcome in terms of pain, associated symptoms, functionality, and complications [Table 1]. [1] For children, the mRS was scored with agespecific modification.…”

Section: Methodsmentioning

confidence: 99%

Functional status of surgically treated pineal cyst patients

Choque-Velasquez

Resendiz-Nieves

Baluszek

et al. 2020

Surgical Neurology International

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Background: Microsurgical removal represents a well-accepted treatment option for symptomatic benign pineal cysts (PCs). However, very few studies have quantitatively evaluated the functional status of surgically treated PC patients. Methods: A detailed analysis of preoperative, immediate postoperative, and long-term clinical and radiological characteristics was performed. The functional status of the patients was categorized using the modified Rankin scale (mRS) and the Chicago Chiari Outcome Scale (CCOS). In addition, a comparative analysis between pediatric and adult patients with PCs was carried out. Results: Overall, pediatric patients experienced better long-term mRS scores than adults. The differences between the pre-, the immediate post-, and the last postoperative mRS of the patients were statistically significant for the total population (P < 0.001). All patients obtained a CCOS of 11 or more, which reflects a good/optimal result after microneurosurgery. The type of the surgical approach was independently associated with the postoperative complications (P < 0.01), more frequently reported with the midline supracerebellar infratentorial (SCIT) approach than with its paramedian modification. Conclusion: The functional status of properly selected symptomatic patients with PCs may improve significantly after their surgical management through a paramedian SCIT approach in sitting position.

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Management Algorithm in Pineal Lesions

Matei¹,

Borha²

2020

Pineal Region Lesions

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Pineal Cyst without Hydrocephalus: Clinical Presentation and Postoperative Clinical Course After Infratentorial Supracerebellar Resection

Cited by 20 publications

References 34 publications

Systematic review of pineal cysts surgery in pediatric patients

Systematic review of pineal cysts surgery in pediatric patients

Functional status of surgically treated pineal cyst patients

Management Algorithm in Pineal Lesions

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