Pitting Corrosion Within Bioreactors for Space Cell-Culture Contaminated by Paenibacillus glucanolyticus, a Case Report

Barravecchia, Ivana; Cesari, Chiara De; Pyankova, Olga V.; Scebba, Francesca; Mascherpa, Marco Carlo; Vecchione, Alessandra; Tavanti, Arianna; Tedeschi, Lorena; Angeloni, Debora

doi:10.1007/s12217-018-9601-1

Cited by 8 publications

(4 citation statements)

References 24 publications

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“…Microbial corrosion is a common form of metal deterioration that negatively affects many industrial applications including petroleum pipelines, offshore platforms and ships, nuclear power plant facilities, medical instruments, and even space stations (Barravecchia et al, 2018;Huang et al, 2021;Yang et al, 2021;Zhang et al, 2022). Nearly 10-20% of total corrosion damage globally, equivalent to approximately US $250-500 billion annually, is attributed to microbial activity (Chugh et al, 2022;Skovhus et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Direct microbial electron uptake as a mechanism for stainless steel corrosion in aerobic environments

Zhou

Zhang

et al. 2022

Water Research

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Section: Introductionmentioning

confidence: 99%

Direct microbial electron uptake as a mechanism for stainless steel corrosion in aerobic environments

Zhou

Zhang

et al. 2022

Water Research

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“…The on-going rise of the space private sector, the increased use of micro-satellites, or even the recent launch of the Chinese Space Station, all provide further launch and testing opportunities that should be harnessed to address at least some of the gaps that we have identified. Perhaps there is also room for technical improvements on reducing some historical resistance toward high-salt experiments in space (due to increased risks of corrosion and clogging), allowing for, e.g., the testing of more live strains in liquid medium rather than just in lyophilized, freeze-dried form ( Barravecchia et al, 2018 ; Rcheulishvili et al, 2020 ).…”

Section: Future Work: Knowledge Gaps and Research Opportunitiesmentioning

confidence: 99%

The archaeal class Halobacteria and astrobiology: Knowledge gaps and research opportunities

McGenity

Rettberg

et al. 2022

Front. Microbiol.

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Water bodies on Mars and the icy moons of the outer solar system are now recognized as likely being associated with high levels of salt. Therefore, the study of high salinity environments and their inhabitants has become increasingly relevant for Astrobiology. Members of the archaeal class Halobacteria are the most successful microbial group living in hypersaline conditions and are recognized as key model organisms for exposure experiments. Despite this, data for the class is uneven across taxa and widely dispersed across the literature, which has made it difficult to properly assess the potential for species of Halobacteria to survive under the polyextreme conditions found beyond Earth. Here we provide an overview of published data on astrobiology-linked exposure experiments performed with members of the Halobacteria, identifying clear knowledge gaps and research opportunities.

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“…All space studies are supported by complex logistics, whose planning is an essential part of the experiments [21][22][23]. The ENDO campaign (mission patch in Supplementary Fig.…”

Section: Sample Preparation Space Launch and Sample Retrievalmentioning

confidence: 99%

“…Cells were cultured as in [21,23], within EUs that were electronically controlled and completed the scientific protocol for both culturing and fixing without human intervention (Kayser Italia, Livorno, Italy). ENDO EUs were used for other space missions with similar configuration [25][26][27][28] and, concisely, consist of a main body and a release system unit (Supplementary Fig.…”

Section: The Experimental Unitmentioning

confidence: 99%

Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways

Barravecchia

Cesari

Forcato

et al. 2021

Cell. Mol. Life Sci.

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Microgravity and space radiation (SR) are two highly influential factors affecting humans in space flight (SF). Many health problems reported by astronauts derive from endothelial dysfunction and impaired homeostasis. Here, we describe the adaptive response of human, capillary endothelial cells to SF. Reference samples on the ground and at 1g onboard permitted discrimination between the contribution of microgravity and SR within the combined responses to SF. Cell softening and reduced motility occurred in SF cells, with a loss of actin stress fibers and a broader distribution of microtubules and intermediate filaments within the cytoplasm than in control cells. Furthermore, in space the number of primary cilia per cell increased and DNA repair mechanisms were found to be activated. Transcriptomics revealed the opposing effects of microgravity from SR for specific molecular pathways: SR, unlike microgravity, stimulated pathways for endothelial activation, such as hypoxia and inflammation, DNA repair and apoptosis, inhibiting autophagic flux and promoting an aged-like phenotype. Conversely, microgravity, unlike SR, activated pathways for metabolism and a pro-proliferative phenotype. Therefore, we suggest microgravity and SR should be considered separately to tailor effective countermeasures to protect astronauts' health.

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Pitting Corrosion Within Bioreactors for Space Cell-Culture Contaminated by Paenibacillus glucanolyticus, a Case Report

Cited by 8 publications

References 24 publications

Direct microbial electron uptake as a mechanism for stainless steel corrosion in aerobic environments

Direct microbial electron uptake as a mechanism for stainless steel corrosion in aerobic environments

The archaeal class Halobacteria and astrobiology: Knowledge gaps and research opportunities

Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways

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