Plain radiography is effective for the detection of calcinosis cutis occurring in association with autoimmune connective tissue disease

Abstract

Radiography detected calcinosis in all patients and is recommended for initial imaging of calcinosis. Multiple morphological patterns of calcification were observed across ACTD subtypes. Further studies should correlate radiological studies with treatment of calcinosis and underlying ACTD.

The Presentation, Assessment, Pathogenesis, and Treatment of Calcinosis in Juvenile Dermatomyositis

“…Conventional radiographs are generally sufficient for identifying calcinosis in the pediatric population and have been recommended as the initial imaging study of choice when there is clinical suspicion for calcinosis [39] (Figure 1). In a case series of 37 patients with autoimmune connective tissue disease and suspected calcinosis, including 17 cases of DM, of whom 7 were children, radiographs were able to detect calcinosis in all patients.…”

“…After 21 months on treatment she had dramatic regression of calcinosis, both clinically and radiographically [87]. A second case of a 3-year-old girl with JDM and multiple subcutaneous lesions and severe intraphalangeal calcinosis showed near resolution radiographically and clinically after 12 months of diltiazem (30 mg/day) [39]. A larger case series of adult patients with SSc-associated calcinosis showed only 3 of 12 SSc patients with improvement radiographically [88].…”

Worsening of calcinosis cutis with teriparatide treatment in two osteoporotic patients

“…Subcutaneous or intracutaneous calcification occurs in 25–40% of patients with this type of systemic sclerosis . Conventional X‐ray analysis is recommended for the initial screening of patients with calcinosis . There is no specific treatment for the management of calcinosis cutis.…”

Diagnostic des calcifications/ossifications non traumatiques de la surface des os et des tissus mous du poignet, de la main et des doigts

“…La calcinose des tissus mous (calcinosis cutis) s'observe fré-quemment en association avec les connectivites et, plus particulièrement, en cas de sclérodermie systémique et de dermatomyosite [23] (Fig. 8).…”