“…To facilitate GS for a genetic improvement program, re-sequencing individuals collected from the farm and the wild, from wide geographical ranges and potentially different phenotypic values, is an effective way to discover genome-wide genetic variation and dissect the commercially important traits in aquaculture. In fact, epigenomics which is the study of heritable changes in gene expression related to modifications of chromatin or DNA protein should be exploited for aquaculture species to elucidate phenotypic interactions with environmental factors such as feeds, water quality, global warming and pathogen exposure (Feinberg, 2008;Kalavacharla et al, 2017;Metzger and Schulte, 2016;Norouzitallab et al, 2014;Roy et al, 2019;Wan et al, 2016).…”