Plant Pathogen Recognition Mediated by Promoter Activation of the Pepper
            <i>Bs3</i>
            Resistance Gene

Römer, Patrick; Hahn, Simone; Jordan, Tina; Strauß, T.; Bonas, Ulla; Lahaye, Thomas

doi:10.1126/science.1144958

Cited by 419 publications

(402 citation statements)

References 20 publications

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“…This suggests that the AvrBs3/PthA effectors might alter plant transcription during infection. Consistent with these structural features, AvrBs3, AvrXa27, PthXo1, PthXo6, and PthXo7 activate host transcription leading to disease susceptibility and/or defense responses (Gu et al, 2005;Yang et al, 2006;Kay et al, 2007;Rö mer et al, 2007;Sugio et al, 2007). Interestingly, AvrBs3 binds directly to plant promoters, and its binding specificity is in part mediated by its central variable repeats (Kay et al, 2007).…”

Section: Introductionmentioning

confidence: 65%

XopD SUMO Protease Affects Host Transcription, Promotes Pathogen Growth, and Delays Symptom Development inXanthomonas-Infected Tomato Leaves

et al. 2008

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We demonstrate that XopD, a type III effector from Xanthomonas campestris pathovar vesicatoria (Xcv), suppresses symptom production during the late stages of infection in susceptible tomato (Solanum lycopersicum) leaves. XopD-dependent delay of tissue degeneration correlates with reduced chlorophyll loss, reduced salicylic acid levels, and changes in the mRNA abundance of senescence- and defense-associated genes despite high pathogen titers. Subsequent structure-function analyses led to the discovery that XopD is a DNA binding protein that alters host transcription. XopD contains a putative helix-loop-helix domain required for DNA binding and two conserved ERF-associated amphiphilic motifs required to repress salicylic acid– and jasmonic acid–induced gene transcription in planta. Taken together, these data reveal that XopD is a unique virulence factor in Xcv that alters host transcription, promotes pathogen multiplication, and delays the onset of leaf chlorosis and necrosis.

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Section: Introductionmentioning

confidence: 65%

XopD SUMO Protease Affects Host Transcription, Promotes Pathogen Growth, and Delays Symptom Development inXanthomonas-Infected Tomato Leaves

et al. 2008

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“…Some resistance genes that recognize TAL effectors are transcriptionally activated through the interaction of corresponding effectors with elements within their promoters (see above). For example, the pepper resistance gene Bs3 is targeted by the Xanthomonas AvrBs3 effector that directly activates its transcription and thereby confers resistance (Romer et al 2007). …”

Section: Recognition Of Pathogen Effectors By Plant Immunoreceptorsmentioning

confidence: 99%

Effector Biology of Plant-Associated Organisms: Concepts and Perspectives

Win

Chaparro-Garcia

Belhaj

et al. 2012

Cold Spring Harbor Symposia on Quantitative Biology

357

329

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Every plant is closely associated with a variety of living organisms. Therefore, deciphering how plants interact with mutualistic and parasitic organisms is essential for a comprehensive understanding of the biology of plants. The field of plant-biotic interactions has recently coalesced around an integrated model. Major classes of molecular players both from plants and their associated organisms have been revealed. These include cell surface and intracellular immune receptors of plants as well as apoplastic and host-cell-translocated (cytoplasmic) effectors of the invading organism. This article focuses on effectors, molecules secreted by plant-associated organisms that alter plant processes. Effectors have emerged as a central class of molecules in our integrated view of plant-microbe interactions. Their study has significantly contributed to advancing our knowledge of plant hormones, plant development, plant receptors, and epigenetics. Many pathogen effectors are extraordinary examples of biological innovation; they include some of the most remarkable proteins known to function inside plant cells. Here, we review some of the key concepts that have emerged from the study of the effectors of plant-associated organisms. In particular, we focus on how effectors function in plant tissues and discuss future perspectives in the field of effector biology.

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“…The TALEs are a family of DNA-binding proteins [3][4][5]. A TALE contains a number of sequence repeats, each recognizing one DNA base.…”

Section: Dear Editormentioning

confidence: 99%

Recognition of methylated DNA by TAL effectors

et al. 2012

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Plant Pathogen Recognition Mediated by Promoter Activation of the Pepper Bs3 Resistance Gene

Cited by 419 publications

References 20 publications

XopD SUMO Protease Affects Host Transcription, Promotes Pathogen Growth, and Delays Symptom Development inXanthomonas-Infected Tomato Leaves

XopD SUMO Protease Affects Host Transcription, Promotes Pathogen Growth, and Delays Symptom Development inXanthomonas-Infected Tomato Leaves

Effector Biology of Plant-Associated Organisms: Concepts and Perspectives

Recognition of methylated DNA by TAL effectors

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