Plants and Lactic Acid Bacteria Combination for New Antimicrobial and Antioxidant Properties Product Development in a Sustainable Manner

Bartkienė, Elena; Lėlė, Vita; Starkutė, Vytautė; Zavistanavičiūtė, Paulina; Zokaitytė, Eglė; Varinauskaite, Ieva; Pileckaite, Greta; Paskeviciute, Laura; Rutkauskaite, Gintare; Kanaporis, Tomas; Dmitrijeva, Laura; Viškelis, Pranas; Santini, Antonello; Ružauskas, Modestas

doi:10.3390/foods9040433

Cited by 20 publications

(13 citation statements)

References 65 publications

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“…Besides, essential oils from A. absinthium were reported to inhibit Listeria monocytogenes, S. aureus and B. cereus with MIC of 0.14, 0.62, and 0.8 µL/mL, respectively and they act by suppressing the biosynthesis of proteins, RNA, DNA, and polysaccharide in the bacterial cells [100]. Recently, Bartkiene et al [101] investigated the antimicrobial activity of the A. absinthium water extract and essential oil, lactic acid bacteria strain, Lactobacillus uvarum LUHS245, and blackcurrants juice preparation BY against Kl. pneumoniae, Salmonella enterica, P. aeruginosa, Acinetobacter baumanni, Proteus mirabilis, methicillin-resistant S. aureus (MRSA) M87fox, Enterococcus faecalis, Enterococcus faecium 103, B. cereus 18 01, Streptococcus mutans, Enterobacter cloacae, Citrobacter freundii, Staphylococcus epidermidis, Staphylococcus haemolyticus, Pasteurella multocida.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

et al. 2020

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Plants have been used since ancient times to cure certain infectious diseases, and some of them are now standard treatments for several diseases. Due to the side effects and resistance of pathogenic microorganisms to antibiotics and most drugs on the market, a great deal of attention has been paid to extracts and biologically active compounds isolated from plant species used in herbal medicine. Artemisia absinthium is an important perennial shrubby plant that has been widely used for the treatment of several ailments. Traditionally, A. absinthium has always been of pharmaceutical and botanical importance and used to manage several disorders including hepatocyte enlargement, hepatitis, gastritis, jaundice, wound healing, splenomegaly, dyspepsia, indigestion, flatulence, gastric pain, anemia, and anorexia. It has also been documented to possess antioxidant, antifungal, antimicrobial, anthelmintic, anti-ulcer, anticarcinogenic, hepatoprotective, neuroprotective, antidepressant, analgesic, immunomodulatory, and cytotoxic activity. Long-term use of A. absinthium essential oil may cause toxic and mental disorders in humans with clinical manifestations including convulsions, sleeplessness, and hallucinations. Combination chemotherapies of artemisia extract or its isolated active constituents with the currently available antibabesial or anti-malarial drugs are now documented to relieve malaria and piroplasmosis infections. The current review examines the phytoconstituents, toxic and biological activities of A. absinthium.

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Section: Antibacterial Activitymentioning

confidence: 99%

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

et al. 2020

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“…Recently, we have investigated some functional products for the active nutraceutical formula which could benefit both humans and animals. Some constituents including bovine colostrum, probiotics and particularly essential oils (EOs), demonstrated good results in vitro [ 5 , 6 , 7 , 8 ]. Essential oils are complex mixtures of volatile compounds isolated from a whole plant or plant part of known taxonomic origin [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

The Influence of Essential Oils on Gut Microbial Profiles in Pigs

Ružauskas

Bartkienė

Stankevičius

et al. 2020

Animals

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In recent years, the intake of ultra-processed foods has increased dramatically worldwide. Missing natural foods in the diet raise the need of biologically active food components that could compensate for this deficiency and help maintain proper immune status. This study used pigs as an animal model for the assessment of the impact of consumption of Origanum vulgare plant extract combined with Mentha piperita and Thymus vulgaris essential oils on microbial profile in intestines. A single group of weaned pigs received basal diet, while the other group basal diet supplemented with plant extract and two essential oils in the form of bilayer tablets prepared using “liquid/solid” phase technology. Metagenomic sequencing was performed with the aim to investigate changes of microbial communities in ileum, caecum, and colon. The results demonstrated that the combination of essential oils was non cytotoxic, and had a positive effect on the microbial composition in the large intestine of pigs due to significant increase in the number of probiotic bacteria. The amount of Lactobacillus was 2.5 times and Bifidobacterium 1.9 times higher in the animal group fed with supplement. The combination, however, had some negative impact on the variety of minor species in the distal part of the ileum. Additional studies need to be performed to obtain knowledge on how combinations of essential oils can change bacterial variety in the proximal part of the gastrointestinal tract.

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“…The co-infection of P. multocida with other pathogens could enhance disease damage to the hosts; e.g., promote secure attachment of the bacteria to the bovine respiratory syncytial virus-infected cells [21] and increase inflammatory cells in the coinfected lesions of bronchopneumonia pigs [22]. Recently, Bartkiene et al developed a combination of a plant extract with a probiotic bacterium Lactobacillus uvarum that could inhibit P. multocida growth in vitro [23]. This finding has led to hypothesize the role of the porcine respiratory tract normal flora on P. multocida growth.…”

Section: Introductionmentioning

confidence: 99%

Interaction study of Pasteurella multocida with culturable aerobic bacteria isolated from porcine respiratory tracts using coculture in conditioned media

2021

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Background The porcine respiratory tract harbours multiple microorganisms, and the interactions between these organisms could be associated with animal health status. Pasteurella multocida is a culturable facultative anaerobic bacterium isolated from healthy and diseased porcine respiratory tracts. The interaction between P. multocida and other aerobic commensal bacteria in the porcine respiratory tract is not well understood. This study aimed to determine the interactions between porcine P. multocida capsular serotype A and D strains and other culturable aerobic bacteria isolated from porcine respiratory tracts using a coculture assay in conditioned media followed by calculation of the growth rates and interaction parameters. Results One hundred and sixteen bacterial samples were isolated from five porcine respiratory tracts, and 93 isolates were identified and phylogenetically classified into fourteen genera based on 16S rRNA sequences. Thirteen isolates from Gram-negative bacterial genera and two isolates from the Gram-positive bacterial genus were selected for coculture with P. multocida. From 17 × 17 (289) interaction pairs, the majority of 220 pairs had negative interactions indicating competition for nutrients and space, while 17 pairs were identified as mild cooperative or positive interactions indicating their coexistence. All conditioned media, except those of Acinetobacter, could inhibit P. multocida growth. Conversely, the conditioned media of P. multocida also inhibited the growth of nine isolates plus themselves. Conclusion Negative interaction was the major interactions among the coculture of these 15 representative isolates and the coculture with P. multocida. The conditioned media in this study might be further analysed to identify critical molecules and examined by the in vivo experiments. The study proposed the possibility of using these molecules in conditioned media to control P. multocida growth.

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Plants and Lactic Acid Bacteria Combination for New Antimicrobial and Antioxidant Properties Product Development in a Sustainable Manner

Cited by 20 publications

References 65 publications

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium)

The Influence of Essential Oils on Gut Microbial Profiles in Pigs

Interaction study of Pasteurella multocida with culturable aerobic bacteria isolated from porcine respiratory tracts using coculture in conditioned media

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