Plasma B-Type Natriuretic Peptide as a Marker of Myocardial Asynchrony

Ciuraszkiewicz, Katarzyna; Janion, Marianna; Dudek, Dariusz; Gawor, Z

doi:10.1159/000193147

Cited by 4 publications

(4 citation statements)

References 36 publications

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“…Very limited data exists on patients with IVCD. Patients with myocardial infarction with IVCD had significantly greater interventricular asynchronies and higher BNP levels than post-myocardial infarction patients without IVCD [ 18 ]. In the Multicenter Unsustained Tachycardia Trial (MUSTT), patients with LBBB or IVCD had lower ejection fractions and a higher prevalence of congestive heart failure than those without these abnormalities.…”

Section: Discussionmentioning

confidence: 99%

Effects of ventricular conduction block patterns on mortality in hospitalized patients with dilated cardiomyopathy: a single-center cohort study

Luo

Fang

et al. 2016

BMC Cardiovasc Disord

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BackgroundVentricular conduction blocks (VCBs) are associated with poor outcomes in patients with known cardiac diseases. However, the prognostic implications of VCB patterns in dilated cardiomyopathy (DCM) patients need to be evaluated. The purpose of this study was to determine all-cause mortality in patients with DCM and VCB.MethodsThis cohort study included 1119 DCM patients with a median follow-up of 34.3 (19.5–60.8) months, patients were then divided into left bundle branch block (LBBB), right bundle branch block (RBBB), intraventricular conduction delays (IVCD) and narrow QRS groups. The all-cause mortality was assessed using Kaplan-Meier survival curves and Cox regression.ResultsOf those 1119 patients, the all-cause mortality rates were highest in patients with IVCD (47.8, n = 32), intermediate in those with RBBB (32.9, n = 27) and LBBB (27.1 %, n = 60), and lowest in those with narrow QRS (19.9 %, n = 149). The all-cause mortality risk was significantly different between the VCB and narrow QRS group (log-rank χ2 = 51.564, P < 0.001). The presence of RBBB, IVCD, PASP ≥ 40 mmHg, left atrium diameter and NYHA functional class were independent predictors of all-cause mortality in DCM patients.ConclusionsOur findings indicate that RBBB and IVCD at admission,but not LBBB, were independent predictors of all-cause mortality in patients with DCM.

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Section: Discussionmentioning

confidence: 99%

Effects of ventricular conduction block patterns on mortality in hospitalized patients with dilated cardiomyopathy: a single-center cohort study

Luo

Fang

et al. 2016

BMC Cardiovasc Disord

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“…2,3,12 BNP was also established as a valuable marker of myocardial asynchrony. 13,14 In recent years, serum BNP levels became useful in monitoring the population of patients with permanent heart stimulation. It was demonstrated that BNP could be of value in screening for heart failure or a prognostic factor of developing heart failure in patients after pacemaker implantation.…”

Section: Introductionmentioning

confidence: 99%

Prognostic value of NT-proBNP levels in patients undergoing permanent pacemaker implantation

Iwańska

Gworys²,

Gawor³

2010

Polish Archives of Internal Medicine

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IntroductIon Permanent cardiac stimulation is a method commonly used in modern cardiology. The available data show that approximately 18,000 of pacing devices are implanted each year in Poland (a mean of 471 per 1 million of inhabitants). 1 Patients who require permanent heart stimulation are at high risk of subsequent cardiovascular events. It is usually related to their advanced age, coexistence of atrial fibrillation or heart failure, to prior myocardial infarction, and to the stimulation itself. Identification of patients who are at risk for developing cardiovascular complications would certainly allow for intensifying pharmaco logical treatment and optimizing the para meters of heart stimulation. B-type natriuretic peptide (BNP) and the N-terminal fragment of BNP prohormone (NT-proBNP) have been established as predictors

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“…We read with great interest the study by Ciuraszkiewicz et al [1] , which showed that plasma levels of B-type natriuretic peptide 6 months after myocardial infarction (MI) depend on both parameters of left ventricle (LV) function and LV asynchrony. The results suggested that B-type natriuretic peptide may serve as a marker of the LV asynchrony in patients with intraventricular conduction defects (IVCD) and preserved LV systolic function.…”

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confidence: 99%