Plasma-treated nano-enabled multimodal coatings made of phototherapeutic molybdenum disulfide and fucoidan prevent catheter-associated urinary tract issues

Liang, Jingtao; Liu, Chia-Hung; Wu, Kevin C.‐W.; Jheng, Pei‐Ru; Chuang, Er‐Yuan

doi:10.1016/j.cej.2023.143749

Cited by 11 publications

(1 citation statement)

References 68 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Such extended-distance transmission of light carries substantial possibilities for biological medical applications necessitating deep light penetration, such as deep tissue diagnosis as well as imaging. Other functional photonic/optical-based biomaterials were developed and applied in the theragnostic vascular diseases [143][144][145][146][147][148][149], urinary system [150], anticancer/translational medicine/characterizations [114,[151][152][153][154], and regenerative medicine applications [145,[155][156][157][158].…”

Section: Cell-constructed Biologically Photonic Waveguidesmentioning

confidence: 99%

Biological Photonic Devices Designed for the Purpose of Bio-Imaging with Bio-Diagnosis

Chuang,

Yu,

Hung

et al. 2023

Photonics

Self Cite

View full text Add to dashboard Cite

The rapid progress in the fields of biomedical and biological photonic sciences has given rise to a substantial demand for biological photonic structures capable of interacting with living systems. These structures are expected to facilitate precise manipulation of incident light at small scales, enabling the detection of sensitive biological signals and the achievement of highly accurate cell structural imaging. The concept of designing biological photonic devices using innate biomaterials, particularly natural entities such as cells, viruses, and organs, has gained prominence. These innovative devices offer the capability of multimodal light manipulation at specific sites, enhancing biological compatibility while minimizing disruptions to the delicate biological microenvironment. This article delves into recent advancements within the realm of biological photonic devices, with a dedicated focus on their applications in bio-imaging and -diagnosis. The central theme revolves around devices derived from biological entities possessing the requisite optical properties, biocompatibility, biofunctionality, and the ability to induce biological effects. These devices encompass a diverse range of optical functionalities, including light generation, transportation, and modulation, all of which play pivotal roles in bio-detection and imaging, thereby contributing notably to the advancement of these fields. The potential future directions and opportunities for the enhancement of biological photonic devices were outlined.

show abstract

Section: Cell-constructed Biologically Photonic Waveguidesmentioning

confidence: 99%

Biological Photonic Devices Designed for the Purpose of Bio-Imaging with Bio-Diagnosis

Chuang,

Yu,

Hung

et al. 2023

Photonics

Self Cite

View full text Add to dashboard Cite

show abstract

Dual‐Layer Nanoengineered Urinary Catheters for Enhanced Antimicrobial Efficacy and Reduced Cytotoxicity

Won,

Lee,

Park

et al. 2024

Adv Healthcare Materials

View full text Add to dashboard Cite

Catheter‐associated urinary tract infection (CAUTI) is the most common healthcare‐associated infection; however, current therapeutic strategies remain insufficient for standard clinical application. A novel urinary catheter featuring a dual‐layer nanoengineering approach using zinc (Zn) and silver nanoparticles (AgNPs) is successfully fabricated. This design targets microbial resistance, minimizes cytotoxicity, and maintains long‐term efficacy. The inner AgNPs layer provides immediate antibacterial effects against the UTI pathogens, while the outer porous Zn layer controls zero‐order Ag release and generates reactive oxygen species, thus enhancing long‐term bactericidal performance. Enhanced antibacterial properties of Zn/AgNPs‐coated catheters are observed, resulting in 99.9% of E. coli and 99.7% of S. aureus reduction, respectively. The Zn/AgNPs‐coated catheter significantly suppresses biofilm with sludge formation compared to AgNP‐coated and uncoated catheters (all, p < 0.05). The Zn/AgNP‐coated catheter in a rabbit model demonstrated a durable, effective barrier against bacterial colonization, maintaining antimicrobial properties during the catheter indwelling period with significantly reduced inflammation and epithelial disruption compared with AgNP and uncoated groups. This innovation has the potential to revolutionize the design of antimicrobial medical devices, particularly for applications requiring long‐term implantation. Although further preclinical studies are required to verify its efficacy and safety, this strategy seems to be a promising approach to preventing CAUTI‐related complications.

show abstract

Functionalized Nanomaterials for Detecting Environmental Pollutants

Dave,

Pandey,

Jain

et al. 2024

ChemistrySelect

View full text Add to dashboard Cite

The environment consists of wide diversity, of which, an integral and most diversifying part is the living organisms, and hence it is imperative to design novel strategies that could alleviate pollutants and detect them at very minute levels. The functionalization of nanomaterials provides a very facile and efficient tool for the design of robust sensors that could detect pollutants that contaminate air, water, and soil. Because of their nanoscale size, these materials have enhanced surface‐to‐volume ratio, which in turn provide more reaction sites for the analyte interaction and enables highly specific and sensitive detection. Different nanomaterials like metal/metal oxide nanoparticles, quantum dots, carbon‐based nanomaterials, and miscellaneous nanomaterials like polymer, dendrimers, metal‐organic frameworks are functionalized with suitable ligands for efficient detection of a wide range of pollutants such as heavy metals, pesticides, industrial wastes, volatile organic compounds, toxic gases, and environmental pathogens with efficient level of sensitivity. In this review, we will briefly discuss different types of functionalized nanomaterials, strategies adopted for their functionalization, detection methodologies pursued for specific sensing and detection of different types of pollutants and their critical analysis, and future outlook.

show abstract

Plasma-treated nano-enabled multimodal coatings made of phototherapeutic molybdenum disulfide and fucoidan prevent catheter-associated urinary tract issues

Cited by 11 publications

References 68 publications

Biological Photonic Devices Designed for the Purpose of Bio-Imaging with Bio-Diagnosis

Biological Photonic Devices Designed for the Purpose of Bio-Imaging with Bio-Diagnosis

Dual‐Layer Nanoengineered Urinary Catheters for Enhanced Antimicrobial Efficacy and Reduced Cytotoxicity

Functionalized Nanomaterials for Detecting Environmental Pollutants

Contact Info

Product

Resources

About