2013
DOI: 10.1021/ac303387a
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Plasmonic Nanorice Antenna on Triangle Nanoarray for Surface-Enhanced Raman Scattering Detection of Hepatitis B Virus DNA

Abstract: The sensitivity and the limit of detection of Raman sensors are limited by the extremely small scattering cross section of Raman labels. Silver nanorice antennae are coupled with a patterned gold triangle nanoarray chip to create spatially broadened plasmonic "hot spots", which enables a large density of Raman labels to experience strong local electromagnetic field. Finite difference time domain simulations have confirmed that the quasi-periodic structure increases the intensity and the area of the surface pla… Show more

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Cited by 145 publications
(121 citation statements)
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“…The ordered Au nanohole array pattern was fabricated on the FTO substrate with nanosphere lithography 40,42 . The FTO substrate was first treated with the acid solution to have a hydrophilic surface.…”
Section: Methodsmentioning
confidence: 99%
“…The ordered Au nanohole array pattern was fabricated on the FTO substrate with nanosphere lithography 40,42 . The FTO substrate was first treated with the acid solution to have a hydrophilic surface.…”
Section: Methodsmentioning
confidence: 99%
“…Recent advances in virus biosensing have been made, especially in fluorescence, 65 light scattering, 66,67 surface-enhanced Raman scattering (SERS), 68,69 electrochemical, 7,34,70 QCM, 71,72 microcantilevers (MCLs), 73,74 and SPR 17,47 sensors. The breakdown structure of "nanobiosensor for viral detection" segmentation is described in Figure 2.…”
Section: Detection Methods Of Virus Biosensorsmentioning
confidence: 99%
“…The sandwich approach uses target DNA-Raman reporter molecules [225,[230][231][232][233][234][235][236][237][238][239][240]. The first report of SERS DNA and RNA detection using sandwich structures was published by Mirkin and co-workers.…”
Section: Sers-based Dna Detectionmentioning
confidence: 99%