Plastic Surgical Solutions for Melkersson-Rosenthal Syndrome

Abstract

: Melkersson-Rosenthal Syndrome (MRS) is a rare granulomatous disease characterized by a triad, including orofacial swelling, facial palsy and lingua plicata with usually recurrent or progressive course. Orofacial swelling, the most often sign of MRS, leads to the both esthetic and functional deformities. Because of its unknown etiology, a rational treatment is difficult and management of MRS still remains symptomatic, aiming at to remove orofacial swelling mainly. Although the many nonsurgical therapies have been mentioned in the literature, none has been proved uniformly and predictably successful to date. In this paper, we present different surgical procedures and their outcomes in a series of 4 cases with MRS. The procedures including mucosa, submucosa and tangential muscle resection, crescent shaped commissuroplasty, and facial liposuction may be considered in surgical armamentarium when orofacial swelling becomes persistent. We think that the plastic surgeons may act more effectively in the management of the syndrome in the future.

Corrección de "labio ondulado" en el síndrome de Melkersson-Rosenthal

“…Diferentes autores proponen una resección transversal del espesor del labio para tratar esta patología (15,17,18). Sin embargo esto lleva a una deformidad en forma de "labio ondulado", es decir, provoca un labio redundante en el que a pesar de que se ha practicado un adelgazamiento, no se ha corregido el exceso horizontal en longitud, corrección que sólo se logra al eliminar una porción del labio en sentido horizontal, tal y como sucede en la técnica que proponemos.…”

Functional and Therapeutic Indications of Liposuction

“…Acceptable results may be achieved in combination with mucosa, submucosa, and tangential muscle resection, as well as crescent shaped commissuroplasty whenever indicated. 67 …”

“…67 Despite the myriad of nonsurgical therapies available for the treatment of MRS, none has proved uniformly and predictably successful to date. 67 Surgical management of MRS has often yielded disappointing results. It is suitable only in severe disfigurement or when the orofacial swelling has become permanent.…”

“…It is suitable only in severe disfigurement or when the orofacial swelling has become permanent. 67 To achieve facial symmetry, subcutaneous fat hypertrophy can be reduced by SAL. Acceptable results may be achieved in combination with mucosa, submucosa, and tangential muscle resection, as well as crescent shaped commissuroplasty whenever indicated.…”

“…67 Correction of orofacial swelling, the most common sign of MRS, is aimed primarily at symptomatic relief of discomfort. 67 Despite the myriad of nonsurgical therapies available for the treatment of MRS, none has proved uniformly and predictably successful to date. 67 Surgical management of MRS has often yielded disappointing results.…”