Platelet Aggregation Inhibitor from Ganoderma lucidum

Abstract

Lucidenic acid A (1) and a new lactone, lucidenolactone (2) were isolated from the fruiting bodies of Ganoderma lucidum. Their structures were elucidated by spectroscopic method and single‐crystal X‐ray analysis. Lucidenolactone (2) showed significant antiplatelet aggregation activity. The NMR spectral data of lucidenic acid A were also reassigned.