Platelet and Brain Fatty acid transfer: Hypothesis on Arachidovic Acid and its relationship to Major Depression

Cocchi, Massimo; Amato, Patrizia; Lucía, Alejandro

doi:10.4081/jbr.2009.4732

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Platelet Membrane Viscosity and Serotonin1

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2012

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“…The high concentration of Arachidonic Acid in platelets is a step limit to its mutual exchange with the brain and, as a result, the Arachidonic acid increases its neuronal concentration, since brain receives Arachidonic Acid also from other sources [30,31].…”

Section: Platelet Membrane Viscosity and Serotoninmentioning

confidence: 99%

Considerations on Blood Platelets: A Neuron’s Mirror for Mood Disorders?

Cocchi¹,

Tonello²,

Gabrielli³

2012

OJBD

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This work aims to be a reflection concerning a remarkable similarity between platelet and neuron. Through a series of experimental tests which have affected the fatty acid composition of the membrane of platelets, it was possible to provide a contribution to the scientific literature, which had already reported strong similarities between platelet and neuron. The work performed could be of great interest to investigate, by studying the interactome of the platelet, the molecular behavior of the neuron.

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Section: Platelet Membrane Viscosity and Serotoninmentioning

confidence: 99%