Platelet Count and Platelet Volume in Patients with CKD

Davis, Otis M.; Kore, Rajshekhar; Moore, Alexandra; Ware, Jerry; Mehta, Jawahar L.; Arthur, John M.; Lynch, Donald R.; Jain, Nishank

doi:10.1681/asn.0000000000000220

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…Consequently, data analysis on platelet function is not commonly performed clinically, and the dataset used in our study, which only collected minimal data for HD quality assessment, does not include information on this. Recent research has explored noncomplex approaches using platelet volume and count to assess thrombosis and bleeding risk; however, further studies are needed [29].…”

Section: Discussionmentioning

confidence: 99%

Clinical Impact of the Use of Warfarin in Patients with Atrial Fibrillation Undergoing Maintenance Hemodialysis

Kang,

Kim,

Kim

et al. 2024

JCM

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Background: We evaluated the impact of warfarin use on the clinical outcomes of patients with atrial fibrillation who were undergoing hemodialysis (HD). Methods: A retrospective analysis was conducted utilizing data from patients undergoing maintenance HD who participated in HD quality assessment programs. Patients who were assigned the diagnostic code for atrial fibrillation (n = 4829) were included and divided into two groups based on the use of warfarin: No group (no warfarin prescriptions (n = 4009)), and Warfarin group (warfarin prescriptions (n = 820)). Results: Cox regression analyses revealed that the hazard ratio for all-cause mortality in the Warfarin group was 1.15 (p = 0.005) in univariate analysis and 1.11 (p = 0.047) in multivariable analysis compared to that of the No group. Hemorrhagic stroke was significantly associated with warfarin use, but no significant association between the use of warfarin and ischemic stroke or cardiovascular events was observed. The subgroup results demonstrated similar trends. Conclusions: Warfarin use is associated with a higher risk of all-cause mortality and hemorrhagic stroke, and has a neutral effect on ischemic stroke and cardiovascular events in patients with atrial fibrillation who are undergoing HD, compared to those who are not using warfarin.

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Section: Discussionmentioning

confidence: 99%

Clinical Impact of the Use of Warfarin in Patients with Atrial Fibrillation Undergoing Maintenance Hemodialysis

Kang,

Kim,

Kim

et al. 2024

JCM

View full text Add to dashboard Cite

show abstract

“…We thank Dr. Daungsupawong et al 1 for their interest in our perspective 2 and for raising concerns related to laboratory quality control and confounding factors in measuring platelet count and volume.…”

mentioning

confidence: 99%