Platelet Distribution Width and Mean Platelet Volume in Idiopathic Pulmonary Arterial Hypertension

An association of platelet indices with blood pressure in Beijing adults

“…[37,38] According to Zheng et al, [18] the larger platelets are more active compared to smaller ones both metabolically and enzymatically, which is more likely to be thrombotic potential. Earlier findings have established that raised PDW and MPV levels are an independent risk factor for myocardial infarction including coronary heart diseases.…”

“…[18,44] Earlier researches stated that an elevated platelet aggregation and activation rose along with the process of hypertension. [18,45,46] Our study experienced that the MPV was significantly associated with higher estimator in SBP, regardless of sex, whereas a negative correlation was observed between MPV and DBP.…”

“…[18,44] Earlier researches stated that an elevated platelet aggregation and activation rose along with the process of hypertension. [18,45,46] Our study experienced that the MPV was significantly associated with higher estimator in SBP, regardless of sex, whereas a negative correlation was observed between MPV and DBP. These findings are consistent with previous studies of Ucar et al [47] and Pusuroglu et al [48] Additionally, there are 2 possible mechanisms that may contribute to increased platelet parameter levels during high blood pressure as suggested by some studies, [47,48] such as firstly, pulmonary vascular endothelial dysfunction was linked with the path mechanisms of hypertension, which might lead to the platelet activation and local thrombosis.…”

“…[12–14] Increased platelet activation and aggregation are involved in the pathogenesis of elevated blood pressure, which is also associated with hypertensive risk factors. [15–18] Many researchers have illustrated that the platelet occupy was an important position in mediating immune response and maintaining the vascular homeostasis, atherosclerosis, and an inflammation. [19–23] Moreover, the use of antiplatelet management therapies in the high blood pressure, the platelets play a pivotal role in the pathogenesis of hypertension.…”

Evaluation of Hemocytometer Parameters as Potential Biomarkers in Benign Multinodular Goiter and Papillary Thyroid Carcinoma

“…Increased NLR and MPV are also associated with inflammatory diseases (23). These parameters were thought to be useful laboratory markers in the diagnosis of these diseases (24)(25)(26).…”