“…For example, using local external quality assessment (EQA) data, the inter-laboratory coefficient of variation (CV) for VWF:RCo averaged~50% for samples tested in the last decade [2]. Although these CVs reflect inter-laboratory variation, and the data from Ardillon et al [18] report on a single laboratory, one could propose that intra-laboratory variation, plus intra-individual variation, may also be either comparable, or perhaps even favourable for the PFA-100, depending on the method in use for the VWF:RCo. For the PFA-100, there is only the one instrument, and generally only two cartridges used for VWD testing.…”