Platelet-Rich Plasma Augments Subcision in Atrophic Acne Scars: A Split-Face Comparative Study

Deshmukh, Nitika S.; Belgaumkar, Vasudha Abhijit

doi:10.1097/dss.0000000000001614

Cited by 34 publications

(34 citation statements)

References 13 publications

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“…All included studies were either a comparative, simple randomized, noncontrolled study, or a nonrandomized, controlled, before‐and‐after study . The included study characteristics are summarized in Table .…”

Section: Resultsmentioning

confidence: 99%

“…In a split‐face trial, Deshmukh et al reported 7 cases of postinflammatory hyperpigmentation (PIH) that occurred as a result of both PRP combined with subcision and subcision alone. These reactions occurred equally on both sides of each patient's face.…”

Section: Resultsmentioning

confidence: 99%

“…All included studies were either a comparative, simple randomized, noncontrolled study, 12,18,19 or a nonrandomized, controlled, beforeand-after study. 13,[20][21][22][23] The included study characteristics are summarized in Table 1. There were 238 participants treated with a combination therapy utilizing PRP as an adjunct.…”

Section: Study Characteristicsmentioning

confidence: 99%

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Platelet‐rich plasma in noninvasive procedures for atrophic acne scars: A systematic review and meta‐analysis

Long

Gupta

et al. 2020

J of Cosmetic Dermatology

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Background The use of platelet‐rich plasma (PRP) combined with noninvasive, nonenergy procedures for atrophic acne scars has shown promise. To date, there has not been a systematic review or meta‐analysis of the effectiveness of this therapy. Aims To use meta‐analysis to compare Goodman and Baron qualitative scores, patient satisfaction outcomes, and adverse effects in patients undergoing combination procedures with PRP, combination procedures without PRP, and noninvasive monotherapy without PRP in the treatment of patients with atrophic acne scars. Patients/Methods The Pubmed and Cochrane library databases were searched for relevant studies published before May 1, 2019. PRISMA guidelines were utilized. Studies that compared the use of PRP in combination with a noninvasive procedure and therapies without PRP for the treatment of atrophic acne scars were included. Cochrane's handbook was utilized to assess the individual biases of the included studies. Publication bias was assessed. Results A total of 311 participants (153 whole‐face participants and 158 split‐face participants) were reviewed across eight included studies. Quantitative analysis of 241 participants across six included studies showed a statistically significant reduction in scar severity scores in favor of microneedling or subcision with PRP (P < .001). Combination therapy with intradermal or topical PRP was significantly more effective than monotherapy alone and combination therapy with an adjunct other than PRP (P < .001 and .001, respectively). Conclusion This systematic review and meta‐analysis demonstrated that microneedling or subcision with PRP produced statistically significant improvement in validated outcomes over microneedling or subcision alone.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Platelet‐rich plasma in noninvasive procedures for atrophic acne scars: A systematic review and meta‐analysis

Long

Gupta

et al. 2020

J of Cosmetic Dermatology

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“…Rolling acne scars responded best followed by boxcars (33.88%). [ 90 ] Bhargava et al [ 91 ] combined PRP with subcision and needling in a randomized study of 30 patients. Significantly more patients in the PRP group had >50% improvement in scars and the downtime was also less.…”

Section: P Latelet-rich P Lasma and mentioning

confidence: 99%

Evidence-based surgical management of post-acne scarring in skin of color

Gupta¹,

Kaur

Patra

et al. 2020

J Cutan Aesthet Surg

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“…Já as cicatrizes faciais ocasionadas por acne afetam 75% dos pacientes. O plasma rico em plaquetas é uma nova opção de tratamento para o controle da acne e suas cicatrizes, devido às suas propriedades antimicrobianas, anti-inflamatórias e rejuvenescedoras (DESHMUKH;BELGAUMKAR, 2018).…”

Section: Introductionunclassified

Avaliação do tratamento de alterações estéticas faciais com uso de um protocolo operacional desenvolvido para a aplicação de plasma rico em plaquetas

Silva

Soares

Rodrigues

et al. 2021

cmbio

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Introdução: o plasma rico em plaquetas é definido como um concentrado de plaquetas autólogas, obtido por centrifugação de sangue total. Trata-se de uma técnica inovadora, simples e de baixo custo, que apresenta muitos benefícios, podendo ser aplicada em diferentes áreas da saúde. Objetivo: a presente pesquisa buscou desenvolver um protocolo operacional padrão para obtenção e aplicação do plasma sanguíneo rico em plaquetas para o tratamento de alterações estéticas faciais. Metodologia: o estudo tratou de uma pesquisa de campo experimental, de caráter qualitativo e quantitativo. Um processo seletivo foi realizado para recrutar pacientes voluntários para o estudo, que foram selecionados de acordo com os critérios de inclusão e exclusão. Através de testes foi possível chegar ao tempo de centrifugação e velocidade ideais para a produção do plasma rico em plaquetas e testá-lo no tratamento de alterações estéticas faciais. Resultados e discussão: as principais mudanças que foram notadas pelos pacientes durante e após o tratamento foram a redução das cicatrizes de acne e aumento da hidratação e viscosidade da pele. A melhora das alterações estéticas tratadas foi notada por 100% dos pacientes, não havendo piora em nenhum paciente. Conclusão: com base nos testes e resultados obtidos, foi possível padronizar um protocolo operacional padrão ideal para a obtenção e aplicação do plasma rico em plaquetas, comprovando sua eficácia no tratamento de alterações estéticas faciais como rugas, flacidez, linhas de expressões acentuadas, acne, cicatrizes de acne, além de ter-se observado uma melhora significativa na hidratação da pele e redução de poros dilatados.

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Platelet-Rich Plasma Augments Subcision in Atrophic Acne Scars: A Split-Face Comparative Study

Abstract: Platelet-rich plasma and subcision act synergistically to improve the appearance of acne scars.

Cited by 34 publications

References 13 publications

Platelet‐rich plasma in noninvasive procedures for atrophic acne scars: A systematic review and meta‐analysis

Platelet‐rich plasma in noninvasive procedures for atrophic acne scars: A systematic review and meta‐analysis

Evidence-based surgical management of post-acne scarring in skin of color

Avaliação do tratamento de alterações estéticas faciais com uso de um protocolo operacional desenvolvido para a aplicação de plasma rico em plaquetas

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