Platinum–Copper Bimetallic Colloid Nanoparticle Cluster Nanozymes with Multiple Enzyme-like Activities for Scavenging Reactive Oxygen Species

Liu, Yan; Qing, Yuling; Jing, Lingcen; Zou, Wenting

doi:10.1021/acs.langmuir.1c00697

Cited by 42 publications

(31 citation statements)

References 41 publications

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“…[51] By a facile one-pot chemical coreduction method, Guo and coworkers prepared platinum-copper bimetallic colloid nanoparticle cluster nanozymes (PVP-PtCuNCs) that possess efficient SOD-like, POD-like, and CAT-like activities, and these enzyme activities mainly decided by the bimetal component and cluster structure. [52] Generally, metals and their complexes have pH-dependent behavior. Moreover, Pt and Pd have better CAT enzyme activity than Au and Ag by comparison with their energy barrier results using theoretical calculation.…”

Section: Metal-based Cat-like Nanozymesmentioning

confidence: 99%

“…[ 51 ] By a facile one‐pot chemical coreduction method, Guo and co‐workers prepared platinum–copper bimetallic colloid nanoparticle cluster nanozymes (PVP‐PtCuNCs) that possess efficient SOD‐like, POD‐like, and CAT‐like activities, and these enzyme activities mainly decided by the bimetal component and cluster structure. [ 52 ]…”

Section: Classification Of Cat‐like Nanozymesmentioning

confidence: 99%

Section: The Catalytic Mechanism Of Cat‐like Nanozymesmentioning

confidence: 99%

mentioning

confidence: 99%

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Catalase‐Like Nanozymes: Classification, Catalytic Mechanisms, and Their Applications

Yao

et al. 2022

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The field of nanozymes has developed rapidly over the past decade. Among various oxidoreductases mimics, catalase (CAT)‐like nanozyme, acting as an essential part of the regulation of reactive oxygen species (ROS), has attracted extensive research interest in recent years. However, CAT‐like nanozymes are not as well discussed as other nanozymes such as peroxidase (POD)‐like nanozymes, etc. Compared with natural catalase or artificial CAT enzymes, CAT‐like nanozymes have unique properties of low cost, size‐dependent properties, high catalytic activity and stability, and easy surface modification, etc., which make them widely used in various fields, especially in tumor therapy and disease treatment. Consequently, there is a great requirement to make a systematic discussion on CAT‐like nanozymes. In this review, some key aspects of CAT‐like nanozymes are deeply summarized as: 1) Typical CAT‐like nanozymes classified by different nanomaterials; 2) The catalytic mechanisms proposed by experimental and theoretical studies; 3) Extensive applications in regard to tumor therapy, cytoprotection and sensing. Therefore, it is prospected that this review will contribute to the further design of CAT‐like nanozymes and optimize their applications with much higher efficiency than before.

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Section: Metal-based Cat-like Nanozymesmentioning

confidence: 99%

Section: Classification Of Cat‐like Nanozymesmentioning

confidence: 99%

Section: The Catalytic Mechanism Of Cat‐like Nanozymesmentioning

confidence: 99%

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confidence: 99%

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Catalase‐Like Nanozymes: Classification, Catalytic Mechanisms, and Their Applications

Yao

et al. 2022

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“…In addition to inorganic nanoparticles and natural antioxidants, metal oxide nanoparticles have been reported to exhibit similar antioxidant enzyme activity to treat inflammation related to kidney injury [104]. [106].…”

Section: Antioxidant Delivery Systems Used For Bone-relatedmentioning

confidence: 99%

Advances in Delivering Oxidative Modulators for Disease Therapy

Wei

Yue

et al. 2022

Research

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Oxidation modulators regarding antioxidants and reactive oxygen species (ROS) inducers have been used for the treatment of many diseases. However, a systematic review that refers to delivery system for divergent modulation of oxidative level within the biomedical scope is lacking. To provide a comprehensive summarization and analysis, we review pilot designs for delivering the oxidative modulators and the main applications for inflammatory treatment and tumor therapy. On the one hand, the antioxidants based delivery system can be employed to downregulate ROS levels at inflammatory sites to treat inflammatory diseases (e.g., skin repair, bone-related diseases, organ dysfunction, and neurodegenerative diseases). On the other hand, the ROS inducers based delivery system can be employed to upregulate ROS levels at the tumor site to kill tumor cells (e.g., disrupt the endogenous oxidative balance and induce lethal levels of ROS). Besides the current designs of delivery systems for oxidative modulators and the main application cases, prospects for future research are also provided to identify intelligent strategies and inspire new concepts for delivering oxidative modulators.

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Enzyme Mimics for Engineered Biomimetic Cascade Nanoreactors: Mechanism, Applications, and Prospects

Zhang

Chen

et al. 2021

Adv Funct Materials

107

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Multiple enzyme-driven biological catalytic cascades occur in living organisms, guiding highly efficient and selective transformations of substrates. Inspired by the merits of these biological catalytic cascade systems, enormous efforts have been devoted to developing novel cascade catalytic systems to mimic biological cascade catalytic reactions over the past few years. Nanozymes, a class of enzyme mimics, are nanomaterials with enzyme-like catalytic activity. The emergence and development of nanozymes has significantly advanced the development of biomimetic cascade nanoreactors. Currently, biomimetic cascade nanoreactors driven by advanced nanozymes have been widely used and exhibit many advantages such as superior cascade catalytic efficiency and high stability, resulting in significant advancements in biosensing and biomedical applications. The latest advances in understanding the cascade catalytic mechanism of nanozyme-engineered biomimetic cascade catalytic nanoreactors and their progressive applications for biosensing and biomedical applications are comprehensively covered here. First, nanozyme and enzyme/nanozyme-engineered biomimetic cascade catalytic nanoreactors are categorized according to their catalytic mechanism and properties. Then, the biosensing and biomedical applications, including cancer therapy, antibacterial activity, antioxidation, and hyperuricemia therapy of the cascade catalytic systems are covered. The conclusion describes the most important challenges and opportunities remaining in this exciting area of research.

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Platinum–Copper Bimetallic Colloid Nanoparticle Cluster Nanozymes with Multiple Enzyme-like Activities for Scavenging Reactive Oxygen Species

Cited by 42 publications

References 41 publications

Catalase‐Like Nanozymes: Classification, Catalytic Mechanisms, and Their Applications

Catalase‐Like Nanozymes: Classification, Catalytic Mechanisms, and Their Applications

Advances in Delivering Oxidative Modulators for Disease Therapy

Enzyme Mimics for Engineered Biomimetic Cascade Nanoreactors: Mechanism, Applications, and Prospects

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