Pleomorphic Adenoma in the Lower Lip: A Case Report and a Review

Nourwali, Ibrahim; Dar‐Odeh, Najla

doi:10.1055/s-0039-1700363

Cited by 12 publications

(13 citation statements)

References 34 publications

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“…4 Pleomorphic adenoma was one the most common tumors found among benign neoplasms. 24 Among salivary gland neoplasms similar findings were reported by Tian et al 25 The etiology of salivary gland tumors is unknown and they comprise 3% of head and neck tumors in the United States. 26 A significant difference was found in relation to mean age of patients with the older people who were more likely to be diagnosed with malignant tumors.…”

Section: Discussionsupporting

confidence: 73%

Trend Analysis of Head and Neck Neoplasms between 2012–2018 in Patients Residing in Al-Madinah, Saudi Arabia: A Retrospective Study

Alsharif

Krsoum

et al. 2021

Eur J Dent

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Objectives This study sought to present a view of head and neck neoplasms (HNN) prevalence with specific focus on sociodemographic determinants in Al-Madinah Province, Saudi Arabia. Materials and Methods This was a hospital-based retrospective study based on retrieval of histopathological data for a period of 6 years between 2012 and 2018. Data was collected from the archives of the Oral and Maxillofacial Pathology Laboratory at King Fahad Hospital (the only referral center for biopsy services) in Al-Madinah City. Statistical Analysis An independent t-test and/or nonparametric (Mann–Whitney U test, chi-squared test) tests were used to determine the differences between groups. Statistical significance was set at the p-value < 0.05. Results Out of 96 patients, a total of 58 patients had valid biopsy data with preoperative diagnosis. Over three quarters of the cases (n = 44) were benign with only 24% were malignant. Males were more likely to be diagnosed with a benign tumor than females (54.5 vs. 45.6%, respectively), and malignancy was also more common in males (64.3 vs. 24.1). A significant difference was found in relation to mean age of older patients who were more likely to be diagnosed with malignant tumors (p = 0.001). Conclusions The findings suggest that most of biopsied HNN cases are benign neoplasms. Age is a significant risk factor for head and neck malignancy in this region. Delays in diagnosis of HNN need to be explored.

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Section: Discussionsupporting

confidence: 73%

Trend Analysis of Head and Neck Neoplasms between 2012–2018 in Patients Residing in Al-Madinah, Saudi Arabia: A Retrospective Study

Alsharif

Krsoum

et al. 2021

Eur J Dent

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“…We conducted a search of the literature on lip PAs (in Japan and worldwide) and found 35 cases described in 31 reports since 2000 (Table 2) (10,11,14-17,19-22,26-39,41). Of the 35 past cases of lip PA, 30 (85.7%) were in the upper lip (10,11,13,15,17,(19)(20)(21)(23)(24)(25)(26)(28)(29)(30)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41) and only five (14.3%) were in the lower lip (14,16,22,27,31). The male-tofemale ratio of the lip PAs was 4:3 (a nonsignificant difference), and the age range was from 10 to 72 years (Table 2).…”

Section: Discussionmentioning

confidence: 99%

Lip pleomorphic adenomas: case series and literature review

Umemori¹,

Ono²,

Kanemoto³

et al. 2022

Gland Surg

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Background: Pleomorphic adenoma (PA) is the most frequent benign salivary gland tumor, but a lip PA is rare. Although this tumor may be definitively diagnosed by imaging or a tissue biopsy if it is reasonably large, PAs on the lip are relatively small, and they present findings that are similar to those of other lip lesions, which can make a preoperative diagnosis difficult. Methods:We analyzed all PAs in the oral region and lesions on the lips treated in our department over the past 20 years, and we discuss them together with the relevant literature.Results: We found that 11.8% (n=6) of the PAs occurred on a lip (upper lip: 9.8%, lower lip: 2.0%), and ~1% of all mass lesions of the lips were PAs. The average size of the lip PAs was 1.5±0.7 cm (range, 0.7-2.2 cm).For preoperative diagnostic assistance, ultrasonography (US) (n=4), magnetic resonance (MR) (n=3), or no imaging (n=2) was used. An excisional biopsy was performed in all cases, and to date, no recurrence or malignant transformation has been observed.Conclusions: Lip PA is relatively rare. Because almost all of these lesions are small, a preoperative diagnosis is more difficult compared to palatal lesions. This tumor is also prone to long-term neglect and has the potential for recurrence and malignant transformation. It is thus necessary to perform an excision that includes the capsule and surrounding tissues, and careful postoperative follow-up should be continued.

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“…Additionally, there were no signs of tumor in peripheral nerves, and this excluded the neurofibroma. Moreover, pleomorphic adenoma is reported more frequently in the upper lip than the lower lip [ 35 ], which is why it was suspected that this lesion was originally pleomorphic adenoma. However, the histological findings ruled out other differential diagnoses and confirm the diagnosis of solitary OAK [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

Solitary Angiokeratoma of the Labial Mucosa: Report of a Rare Case and Literature Review

2022

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Oral angiokeratoma is a rare vascular lesion that has various clinical presentations. It usually occurs as part of generalized angiokeratoma and rarely appears as a solitary lesion with no underlying systemic diseases. Only 33 cases were reported so far worldwide. In this case report, we present a rare case of isolated solitary oral angiokeratoma in a 22-year-old female patient, which is the first case to be reported in the labial mucosa that has been treated successfully by surgical excision.

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Pleomorphic Adenoma in the Lower Lip: A Case Report and a Review

Cited by 12 publications

References 34 publications

Trend Analysis of Head and Neck Neoplasms between 2012–2018 in Patients Residing in Al-Madinah, Saudi Arabia: A Retrospective Study

Trend Analysis of Head and Neck Neoplasms between 2012–2018 in Patients Residing in Al-Madinah, Saudi Arabia: A Retrospective Study

Lip pleomorphic adenomas: case series and literature review

Solitary Angiokeratoma of the Labial Mucosa: Report of a Rare Case and Literature Review

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